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Organ Allocation for Transplantation in the USA and Korea: The Changing Roles of Equity and Utility

Bollinger , Cho WH

Realizing the promise and managing the success of organ transplantation requires the creation of unique institutions. An Organ Procurement and Transplant Network (OPTN) must be capable of increasing the supply...
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Regulatory T Cells - An Emerging Role in Transplantation

Feng G, Wood K

No abstract available.
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FTY720: Mechanism of Action and Potential Benefit in Organ Transplantation

Brinkmann

FTY720 is a novel immunomodulator that has proven effective in animal models of transplantation and autoimmunity, has achieved promising results in Phase I and Phase II studies of renal transplantation...
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Chronic Cyclosporine Nephrotoxicity: New Insights and Preventive Strategies

Li C, Lim SW, Sun BK, Yang CW

Cyclosporine (CsA) has improved patient and graft survival rates following solid-organ transplantation and has been increasingly applied with significant clinical benefits in the management of autoimmune diseases. However, the clinical...
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FK778, A Synthetic Malononitrilamide

Fitzsimmons WE, First MR

FK778 is a synthetic malononitrilamide (MNA) that has been demonstrated to have both both immunosuppressive and anti-proliferative activities. The MNAs inhibit both T-cell and B-cell function by blocking de novo...
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Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Korea

Cheong HI, Jo SK, Yoon SS, Cho H, Kim JS, Kim YO, Koo JR, Park Y, Park YS, Shin JI, Yoo KH, Oh D

Atypical hemolytic uremic syndrome (aHUS) is a rare syndrome characterized by micro-angiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury. The major pathogenesis of aHUS involves dysregulation of the complement system....
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