- Molecular targeted therapy for advanced gastric cancer
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Kim JG
- KMID: 1501767
- Korean J Intern Med.
- 2013 Mar;28(2):149-155.
- doi: 10.3904/kjim.2013.28.2.149
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the... -
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- APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
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Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK
- KMID: 2155371
- Exp Mol Med.
- 2014 Jul;46(7):e106.
- doi: 10.1038/emm.2014.42
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as... -
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- One target, different effects: a comparison of distinct therapeutic antibodies against the same targets
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Shim H
- KMID: 1123366
- Exp Mol Med.
- 2011 Oct;43(10):539-549.
- doi: 10.3858/emm.2011.43.10.063
To date, more than 30 antibodies have been approved worldwide for therapeutic use. While the monoclonal antibody market is rapidly growing, the clinical use of therapeutic antibodies is mostly limited... -
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