- Stem Cell Therapy for Bronchopulmonary Dysplasia: Bench to Bedside Translation
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Ahn SY, Chang YS, Park WS
- KMID: 2155461
- J Korean Med Sci.
- 2015 May;30(5):509-513.
- doi: 10.3346/jkms.2015.30.5.509
Bronchopulmonary dysplasia (BPD), a chronic lung disease affecting very premature infants, is a major cause of mortality and long-term morbidities despite of current progress in neonatal intensive care medicine. Though... -
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- Clinical Application of Adipose Stem Cells in Plastic Surgery
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Kim YJ, Jeong JH
- KMID: 1774450
- J Korean Med Sci.
- 2014 Apr;29(4):462-467.
- doi: 10.3346/jkms.2014.29.4.462
Adipose stem cells (ASCs) are a type of adult stem cells that share common characteristics with typical mesenchymal stem cells. In the last decade, ASCs have been shown to be... -
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- Clinical applications of mesenchymal stem cells
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Kim N, Cho SG
- KMID: 1503774
- Korean J Intern Med.
- 2013 Jul;28(4):387-402.
- doi: 10.3904/kjim.2013.28.4.387
Mesenchymal stem cells (MSCs) are self-renewing, multipotent progenitor cells with multilineage potential to differentiate into cell types of mesodermal origin, such as adipocytes, osteocytes, and chondrocytes. In addition, MSCs can... -
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- Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
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Yoo SW, Kim SS, Lee SY, Lee HS, Kim HS, Lee YD, Suh-Kim H
- KMID: 1094118
- Exp Mol Med.
- 2008 Aug;40(4):387-397.
- doi: 10.3858/emm.2008.40.4.387
Mesenchymal stem cells (MSCs) secrete bioactive factors that exert diverse responses in vivo. In the present study, we explored mechanism how MSCs may lead to higher functional recovery in the... -
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- Mesenchymal stem cell therapy for liver fibrosis
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Eom YW, Shim KY, Baik SK
- KMID: 2381555
- Korean J Intern Med.
- 2015 Sep;30(5):580-589.
- doi: 10.3904/kjim.2015.30.5.580
Currently, the most effective treatment for end-stage liver fibrosis is liver transplantation; however, transplantation is limited by a shortage of donor organs, surgical complications, immunological rejection, and high medical costs.... -
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- Mesenchymal stem cells: environmentally responsive therapeutics for regenerative medicine
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Murphy MB, Moncivais , Caplan AI
- KMID: 2154273
- Exp Mol Med.
- 2013 Nov;45(11):e54.
Mesenchymal stem cells (MSCs) are partially defined by their ability to differentiate into tissues including bone, cartilage and adipose in vitro, but it is their trophic, paracrine and immunomodulatory functions... -
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- Transplantation of Mesenchymal Stem Cells for Acute Spinal Cord Injury in Rats: Comparative Study between Intralesional Injection and Scaffold Based Transplantation
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Kim YC, Kim YH, Kim JW, Ha KY
- KMID: 2468268
- J Korean Med Sci.
- 2016 Sep;31(9):1373-1382.
- doi: 10.3346/jkms.2016.31.9.1373
Experimental stem cell therapy for spinal cord injury (SCI) has been extensively investigated. The selection of effective cell transplantation route is also an important issue. Although various types of scaffold... -
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- Preclinical Study of Cell Therapy for Osteonecrosis of the Femoral Head with Allogenic Peripheral Blood-Derived Mesenchymal Stem Cells
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Fu Q, Tang NN, Zhang Q, Liu Y, Peng JC, Fang N, Yu LM, Liu JW, Zhang T
- KMID: 2374136
- Yonsei Med J.
- 2016 Jul;57(4):1006-1015.
- doi: 10.3349/ymj.2016.57.4.1006
PURPOSE: To explore the value of transplanting peripheral blood-derived mesenchymal stem cells from allogenic rabbits (rPBMSCs) to treat osteonecrosis of the femoral head (ONFH). MATERIALS AND METHODS: rPBMSCs were separated/cultured from... -
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- Stem Cell Therapy for the Treatment of Hip Osteonecrosis: A 30-Year Review of Progress
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Hernigou P, Trousselier M, Roubineau , Bouthors C, Chevallier N, Rouard H, Flouzat-Lachaniette CH
- KMID: 2363939
- Clin Orthop Surg.
- 2016 Mar;8(1):1-8.
- doi: 10.4055/cios.2016.8.1.1
Avascular necrosis of the femoral head is caused by a multitude of etiologic factors and is associated with collapse with a risk of hip arthroplasty in younger populations. A focus... -
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- Transplantation of Neural Differentiated Human Mesenchymal Stem Cells into the Cochlea of an Auditory-neuropathy Guinea Pig Model
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Cho YB, Cho HH, Jang S, Jeong HS, Park JS
- KMID: 1777878
- J Korean Med Sci.
- 2011 Apr;26(4):492-498.
- doi: 10.3346/jkms.2011.26.4.492
The aim of this study was to determine the effects of transplanted neural differentiated human mesenchymal stem cells (hMSCs) in a guinea pig model of auditory neuropathy. In this study,... -
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- In vitro migration capacity of human adipose tissue-derived mesenchymal stem cells reflects their expression of receptors for chemokines and growth factors
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Baek SJ, Kang SK, Ra JC
- KMID: 1123372
- Exp Mol Med.
- 2011 Oct;43(10):596-603.
- doi: 10.3858/emm.2011.43.10.069
The homing properties of adipose tissue-derived mesenchymal stem cells (AdMSCs) have stimulated intravenous applications for their use in stem cell therapy. However, the soluble factors and corresponding cellular receptors responsible... -
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- Intratracheal Administration of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in a Patient with Acute Respiratory Distress Syndrome
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Chang Y, Park SH, Huh JW, Lim CM, Koh Y, Hong SB
- KMID: 1734934
- J Korean Med Sci.
- 2014 Mar;29(3):438-440.
- doi: 10.3346/jkms.2014.29.3.438
Umbilical cord blood (UCB)-derived mesenchymal stem cells (MSCs) have been introduced as a possible therapy in acute lung injury and acute respiratory distress syndrome (ARDS). This case history is reported... -
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- Long-Term (Postnatal Day 70) Outcome and Safety of Intratracheal Transplantation of Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Neonatal Hyperoxic Lung Injury
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Ahn SY, Chang YS, Kim SY, Sung DK, Kim ES, Rime SY, Yu WJ, Choi SJ, Oh WI, Park WS
- KMID: 1503905
- Yonsei Med J.
- 2013 Mar;54(2):416-424.
- doi: 10.3349/ymj.2013.54.2.416
PURPOSE: This study was performed to evaluate the long-term effects and safety of intratracheal (IT) transplantation of human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) in neonatal hyperoxic lung injury... -
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- Establishment of Efficacy and Safety Assessment of Human Adipose Tissue-Derived Mesenchymal Stem Cells (hATMSCs) in a Nude Rat Femoral Segmental Defect Model
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Choi HJ, Kim JM, Kwon E, Che JH, Lee JI, Cho SR, Kang SK, Ra JC, Kang BC
- KMID: 1777877
- J Korean Med Sci.
- 2011 Apr;26(4):482-491.
- doi: 10.3346/jkms.2011.26.4.482
Human adipose tissue-derived mesenchymal stem cell (hATMSC) have emerged as a potentially powerful tool for bone repair, but an appropriate evaluation system has not been established. The purpose of this... -
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- Canine adipose tissue-derived mesenchymal stem cells ameliorate severe acute pancreatitis by regulating T cells in rats
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Kim HW, Song WJ, Li Q, Han SM, Jeon KO, Park SC, Ryu MO, Chae HK, Kyeong K, Youn HY
- KMID: 2412610
- J Vet Sci.
- 2016 Dec;17(4):539-548.
- doi: 10.4142/jvs.2016.17.4.539
Severe acute pancreatitis (SAP) is associated with systemic complications and high mortality rate in dogs. Mesenchymal stem cells (MSCs) have been investigated for their therapeutic potential in several inflammation models.... -
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- Evaluation of Engraftment of Superparamagnetic Iron Oxide-Labeled Mesenchymal Stem Cells Using Three-Dimensional Reconstruction of Magnetic Resonance Imaging in Photothrombotic Cerebral Infarction Models of Rats
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Shim J, Kwak BK, Jung J, Park S
- KMID: 2155527
- Korean J Radiol.
- 2015 Jun;16(3):575-585.
- doi: 10.3348/kjr.2015.16.3.575
OBJECTIVE: To evaluate engraftment by visualizing the location of human bone marrow-derived mesenchymal stem cells (hBM-MSCs) three-dimensionally in photothrombotic cerebral infarction (PTCI) models of rats. MATERIALS AND METHODS: Magnetic resonance imaging... -
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- Long-Term Effects of Bone Marrow-Derived Mesenchymal Stem Cells in Dextran Sulfate Sodium-Induced Murine Chronic Colitis
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Lee HJ, Oh SH, Jang HW, Kwon JH, Lee KJ, Kim CH, Park SJ, Hong SP, Cheon JH, Kim TI, Kim WH
- KMID: 2411969
- Gut Liver.
- 2016 May;10(3):412-419.
- doi: 10.5009/gnl15229
BACKGROUND/AIMS: Bone marrow-derived mesenchymal stem cells (BM-MSCs) have shown beneficial effects in experimental colitis models, but the underlying mechanisms are not fully understood. We investigated the long-term effects of BM-MSCs,... -
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- Clinical Results of Auto-Iliac Cancellous Bone Grafts Combined with Implantation of Autologous Bone Marrow Cells for Osteonecrosis of the Femoral Head: A Minimum 5-Year Follow-Up
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Kang JS, Moon KH, Kim BS, Kwon DG, Shin SH, Shin BK, Ryu DJ
- KMID: 1503918
- Yonsei Med J.
- 2013 Mar;54(2):510-515.
- doi: 10.3349/ymj.2013.54.2.510
PURPOSE: There are no reports about bone graft and cell therapy for the osteonecrosis of femoral head (ONFH). We prospectively evaluated the clinical results of auto-iliac cancellous bone grafts combined... -
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- Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages
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Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, Kim YS, Ahn Y
- KMID: 2155335
- Exp Mol Med.
- 2014 Jan;46(1):e70.
- doi: 10.1038/emm.2013.135
Mesenchymal stem cells (MSCs) have been widely studied for their applications in stem cell-based regeneration. During myocardial infarction (MI), infiltrated macrophages have pivotal roles in inflammation, angiogenesis and cardiac remodeling.... -
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- Optimal Dose and Timing of Umbilical Stem Cells Treatment in Pulmonary Arterial Hypertensive Rats
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Lee H, Kim KC, Choi SJ, Hong YM
- KMID: 2419115
- Yonsei Med J.
- 2017 May;58(3):570-580.
- doi: 10.3349/ymj.2017.58.3.570
PURPOSE: Pulmonary arterial hypertension (PAH) is a fatal disease which is characterized by an increase in pulmonary arterial pressure leading to increases in right ventricular afterload. Human umbilical cord blood... -
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