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Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation

Kim JY, Son YO, Park SW, Bae JH, Chung JS, Kim HH, Chung BS, Kim SH, Kang CD

  • KMID: 1098081
  • Exp Mol Med.
  • 2006 Oct;38(5):474-484.
In this study, we have investigated if current cancer therapeutic modalities including hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in human cancer cell lines. The expressions...
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Development of ligand-dependent regulatory system and its application to gene therapy of insulin-dependent diabetes mellitus

Kim JM, Kim SJ, Lee HC, Kim KS

  • KMID: 1110122
  • Exp Mol Med.
  • 2006 Aug;38(4):385-392.
To develop an inducible expression system, the enhanced artificial nuclear receptors and target reporters were constructed. Artificial nuclear receptors were generated by fusing three domains, consisting of DNA-binding domain (DBD)...
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