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Deletion of Rb1 gene in late osteosarcoma from survivor of unilateral retinoblastoma: a case report

Lee SY, Jeon DG, Lee JS, Hwang CS, Huh K, Lee TW, Hong SI

It has been well known that the survivors of retinoblastoma are prone to have osteosarcoma. But the secondary tumor usually occurs in bilateral, hereditary type of retinoblastoma. We report one...
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Loss of retinoblastoma gene and amplification of N-myc gene in retinoblastoma

Choi SW, Lee TW, Yang SW, Hong WS, Kim CM, Lee JO

We have analyzed paired samples of genomic DNA from peripheral leukocyte and primary tumor tissue from nine patients with retinoblastoma (RB) and from two RB cell lines, WERI-Rb-1 and Y79,...
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Clinical significance of molecular genetic changes in sporadic invasive pituitary adenomas

Nam DH, Song SY, Park KS, Kim MH, Suh YL, Lee JI, Kim JS, Hong SC, Shin HJ, Park K, Eoh W, Kim JH

  • KMID: 938873
  • Exp Mol Med.
  • 2001 Sep;33(3):111-116.
Several molecular and genetic changes have been found in pituitary adenomas. We looked for correlations between these changes and the degree of invasiveness of the tumors. The invasiveness of 11...
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Loss of heterozygosity on chromosome 10, 13q(Rb), 17p, and p53 gene mutations in human brain gliomas

Lee SH, Kim JH, Rhee CH, Kang YS, Lee JH, Hong SI, Choi KS

Using the methods of restriction fragment length polymorphism (RFLP) and single strand conformation polymorphism (SSCP) analyses, we have examined 33 cases of human gliomas with various malignant grades to detect...
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