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Analysis of the Stability of Urea in Dried Blood Spots Collected and Stored on Filter Paper

Quraishi R, Lakshmy R, Mukhopadhyay AK, Jailkhani

The ability to use dry blood spots (DBSs) on filter paper for the analysis of urea levels could be an important diagnostic tool for areas that have limited access to...
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Multiplex Assay of Second-Line Anti-Tuberculosis Drugs in Dried Blood Spots Using Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometry

Lee K, Jun SH, Han M, Song SH, Park JS, Lee JH, Park KU, Song J

As dried blood spots (DBSs) have various advantages over conventional venous blood sampling, some assays for detection of one or two anti-tuberculosis (TB) drugs in DBSs have been developed. However,...
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Analysis of Acid Sphingomyelinase Activity in Dried Blood Spots Using Tandem Mass Spectrometry

Legnini E, Orsini JJ, Muhl A, Johnson B, Dajnoki A, Bodamer OA

BACKGROUND: Niemann Pick disease (NP) is a rare, lysosomal storage disorder due to deficiency of the intra-lysosomal enzyme acid sphingomyelinase (ASM) resulting in intracellular accumulation of sphingomyelin. We evaluated a...
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Analysis of Lyso-Globotriaosylsphingosine in Dried Blood Spots

Johnson B, Mascher H, Mascher D, Legnini E, Hung CY, Dajnoki A, Chien YH, Marodi L, Hwu WL, Bodamer OA

Recently, lyso-globotriaosylsphingosine (lyso-Gb3) was found to be elevated in plasma of treatment naive male patients and some female patients with Fabry Disease (FD). This study tested whether lyso-Gb3 could be...
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