- Current state-of-the-art in human cell transformation in culture
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Rhim JS
- KMID: 1729586
- Yonsei Med J.
- 1991 Sep;32(3):195-206.
- doi: 10.3349/ymj.1991.32.3.195
The immortalization and transformation of cultured human cells has far-reaching implications for both cell and cancer biology. Human cell transformation studies will increase our understanding of the mechanisms underlying carcinogenesis... -
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- Hairy cell transformation of human peripheral blood lymphocytes by Coxiella burnetii
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Lee WY
- KMID: 1107401
- Yonsei Med J.
- 1993 Mar;34(1):11-21.
- doi: 10.3349/ymj.1993.34.1.11
Hairy cell (HC) transformation of human peripheral blood lymphocytes (PBL) by Coxiella burnetii was studied to clarify the significance of persistency of C. burnetii in a hairy cell line (designated... -
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- Ectopic Over-expression of Oncogene Pim-2 Induce Malignant Transformation of Nontumorous Human Liver Cell Line L02
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Ren K, Duan W, Shi Y, Li B, Liu Z, Gong J
- KMID: 1792950
- J Korean Med Sci.
- 2010 Jul;25(7):1017-1023.
- doi: 10.3346/jkms.2010.25.7.1017
In order to prove that ectopic over-expression of Pim-2 could induce malignant transformation of human liver cell line L02, three groups of cells were set up including human liver cell... -
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- Radiologic findings of dysplastic nodule
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Han JK, Eun HW, Kim SH
- KMID: 760789
- Korean J Hepatol.
- 2008 Jun;14(2):231-234.
- doi: 10.3350/kjhep.2008.14.2.231
No abstract available. -
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- A Rare Case of Transformation of Childhood Myelodysplastic Syndrome to Acute Lymphoblastic Leukemia
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Koh YR, Cho EH, Park SS, Park MY, Lee SM, Kim IS, Lee EY
- KMID: 1781313
- Ann Lab Med.
- 2013 Mar;33(2):130-135.
- doi: 10.3343/alm.2013.33.2.130
Transformation of MDS into ALL during childhood is extremely rare. We report a rare case of an 8-yr-old girl who presented with refractory cytopenia of childhood (RCC) that transformed into... -
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- The effect of telomerase expression on the escape from M2 crisis in virus-transformed human retinal pigment epithelial cells
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Park JK, Kim BH, Han YS, Park IK
- KMID: 1081459
- Exp Mol Med.
- 2002 May;34(2):107-113.
Transformation with viral oncogene extends the lifespan of normal cells beyond replicative senescence called M1, but most of them eventually succumb to second crisis called M2 when telomeres become critically... -
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- Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis
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Wang Z, Bhattacharya N, Weaver M, Petersen K, Meyer M, Gapter L, Magnuson N
- KMID: 1119212
- J Vet Sci.
- 2001 Dec;2(3):167-179.
Pim-1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from moloney murine leukemia virus (MuLV)-induced T-cell lymphomas in mice,... -
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- Allogeneic Bone Marrow Transplantation in Shwachman-Diamond Syndrome with Malignant Myeloid Transformation: A Case Report
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Park SY, Chae MB, Kwack YG, Lee MH, Kim IH, Kim YS, Kim CS
- KMID: 759611
- Korean J Intern Med.
- 2002 Sep;17(3):204-206.
Shwachman-Diamond syndrome (SDS) is a rare genetic disorder of unknown pathogenesis involving exocrine pancreatic insufficiency and hematological and skeletal abnormalities. About 25% of patients develop hematopoietic malignancies. We report... -
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- Study on mechanism of multistep hepatotumorigenesis in rat: development of hepatotumorigenesis
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Ha WS, Kim CK, Song SH, Kang CB
- KMID: 1103507
- J Vet Sci.
- 2001 Apr;2(1):53-58.
With the aim of establishing bio-indices for the development of multistep hepatotumorigenesis, rats were fed water containing 0.01% diethylnitrosamine (DEN) ad libitum for 13 weeks. This treatment with DEN only... -
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- Transforming variant of Met receptor confers serum independence and anti-apoptotic property and could be involved in the mouse thymic lymphomagenesis
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Baek CM, Jeon SH, Jang JJ, Lee BS, Lee JH
- KMID: 1094072
- Exp Mol Med.
- 2004 Aug;36(4):283-291.
Met tyrosine kinase receptor, the receptor of hepatocyte growth factor/scatter factor (HGF/SF), is present in mouse tissues as two major isoforms differing by a 47-aminoacid segment in the juxtamembrane domain... -
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