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Pathogenic free-living amoebae

Im KI

Studies on pathogenic free-living amoebae performed in Korea were briefly reviewed. One strain of Naegleria fowleri was isolated from the sewage, and 3 strains of Acanthamoeba culbertsoni from a reservoir...
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The effect of active immunization with Acanthamoeba culbertsoni in mice born to immune mother

Kong HH, Seo SA, Shin CO, Im KI

Acanthamoeba culbertsoni is a pathogenic free-living amoeba causing primary amoebic meningoencephalitis (PAME) in human and mouse. Several reports on the immune responses in mice with this amoebic infection have been...
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Cell-mediated immunity in experimental amoebic meningoencephalitis

Im KI, Chung PR, Kim TU

Cell-mediated and humoral immune reactions in mice infected with pathogenic Acanthamoeba culbertsoni were observed according to the period of time after amoebic infection by intranasal inoculation. The degrees of blastogenesis...
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Natural killer cell activity in Naegleria fowleri infected mice

Lee KR, Shin CO, Im K

The natural killer (NK) cell activity of splenocytes and recycling capacity of NK cells were observed by combining the 51Cr-release cytotoxicity assay and single cell cytotoxicity assay against YAC-1. The...
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The effect of silica on the development of experimental Acanthamoeba meningoencephalitis with reference to the macrophage role in mice

Lee HS, Shin HJ, La MS, Im K

The role of macrophages was observed in intranasally infected C3H/HeJ mice with trophozoites (3 x 10(5)) of Acanthamoeba culbertsoni which was a kind of free-living amoebae inducing meningoencephalitis in human...
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Interleukin-2 production and alteration of T cell subsets in mice infected with Naegleria fowleri

Lyu CJ, Shin CO, Im K

Naegleria fowleri is the cause of primary amoebic meningoencephalitis in man. IL-2 levels after stimulation of T lymphocytes by PHA or N. fowleri lysates, the amounts of T lymphocyte...
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Natural killer cell activity in mice infected with Acanthamoeba culbertsoni

Hyun DK, Shin CO, Im K

The natural killer cell activity of splenocytes and TBC, active NK cells, recycling capacity of natural killer cells were observed by means of both the 51Cr-release cytotoxicity assay and single...
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Natural killer cell activity in mice infected with free-living amoeba with reference to their pathogenicity

Kim KH, Shin CO, Im K

The purpose of this observation was to investigate the natural killer cell activities in mice infected with pathogenic free-living amoeba, Naegleria fowleri and Acanthamoeba culbertsoni according to the infection doses,...
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The protective effects of monoclonal antibodies in mice from Naegleria fowleri infection

Soh EY, Shin HJ, Im K

Protective effects of monoclonal antibodies against N. fowleri were comparatively studied. BALB/c mice were treated with two types of monoclonal antibodies, Nf 2 and Nf 154, before and after the...
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Resistance to Naegleria fowleri infection passively acquired from immunized splenocyte, serum or milk

Ahn MH, Min DY

A pathogenic free-living amoeba, Naegleria fowleri, causes primary amoebic meningoencephalitis to human and experimental animals. This infection is rare, but the mortality is very high. Nowadays, drug treatment or active...
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Cell-mediated immunity in mice infected with Acanthamoeba culbertsoni

Kim MJ, Shin CO, Im KI

Observations were made on the differences of cell-mediated responses in mice of three infection groups differently scheduled in their severity with pathogenic Acanthamoeba culbertsoni. Infections were done by dropping 5...
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Studies on the cell-mediated immunity in experimental Naegleria spp. infections

Lee SG, Shin HJ, Im KI

Observations were made on the differences in cell-mediated immune responses in the mice infected with strongly pathogenic Naegleria fowleri ITMAP 359, weakly pathogenic Naegleria jadini 0400, or non-pathogenic Naegleria gruberi...
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