J Korean Neurosurg Soc.  1998 Dec;27(12):1746-1750.

Extradural Granulocytic Sarcoma in the Cervical Spine

• Yang KH
• Kim YS
• Choi IS
• Bak KH
• Kim JM
• Kim CH
• Ko Y
• Oh SH
• Oh SJ
• Kim KM
• Kim NK

Abstract

Granulocytic sarcoma is an uncommon tumor composed of immature cells of the granulocytic series, occurring in patients with acute myelogenous leukemia and blast crisis of chronic myelogenous leukemia. It may be rarely preceded by an acute myelogenous leukemia and follows an unformly fatal course. We report a case of granulocytic sarcoma of extradural space presenting as the spinal cord compression without any evidence of leukemia in the peripheral blood. The tumor was located extraduraly in the C6-C7 area compressing the dural sac and spinal cord. After left hemilaminectomy of C6 and C7, this mass was removed completely. Postoperatively, symptoms and signs were improved. At the postoperative 10th day, the patient lost consciousness and peripheral blood study showed the findings of acute myelogenous leukemia. Thereafter, the patient received chemotherapy with Ara-C and Daunorubicin, but hematologic remission was not obtained completely. After 4 months, he revisited our hospital owing to fever, and the septic shock was encountered. The patient died of sepsis.

Keyword

Extradural mass; Granulocytic sarcoma; Cervical spine; Leukemia

MeSH Terms

Blast Crisis
Consciousness
Cytarabine
Daunorubicin
Drug Therapy
Fever
Humans
Leukemia
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Leukemia, Myeloid, Acute
Sarcoma, Myeloid*
Sepsis
Shock, Septic
Spinal Cord
Spinal Cord Compression
Spine*
Cytarabine
Daunorubicin