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Biphenotypic blast crisis of chronic myelopenous leukemia

Won DI, Kim BS, Nam CH, Doh YJ, Kwon OH, Min YH

  • KMID: 1685004
  • Korean J Clin Pathol.
  • 1992 Sep;12(3):337-340.
No abstract available.
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A Case of Myeloid Blast Crisis of Atypical Chronic Myelogenous Leukemia

Cho HS, Lee CH, Kim KD, Lee KH, Bae SH, Cho D, Ryang DW

  • KMID: 2252410
  • Korean J Hematol.
  • 2003 Aug;38(3):200-204.
Atypical chronic myelogenous leukemia (aCML) has dysplastic as well as proliferative features in most instance and rarely evolves to blast crisis, so it is considered as a distinct clinical entity...
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Pediatric chronic myeloid leukemia with B-cell lymphoid blast crisis at presentation

Iyer P, Carey P, Bown N, Samarasinghe S

No abstract available.
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Extramedullary blast crisis of secondary CML accompanying marrow fibrosis

Go JH, Park J

No abstract available.
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Acute megakaryoblastic blast crisis as a presentation manifestation of chronic myelogenous leukemia

Bhattacharya JB, Gupta R, Samadhiya

No abstract available.
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The incidence of ABL Deletion on Derivative 9 Chromosome in Chronic Myelogenous Leukemia by Interphase Fluorescence In Situ Hybridization and its Association with Progression to Blast Crisis

Jeong S, Lee DS, See CJ, Ko EK, Park S, Cho HI

  • KMID: 2225972
  • Korean J Clin Pathol.
  • 2000 Dec;20(6):521-526.
BACKGROUND: Philadelphia(Ph) chromosome is found in about 95 percent of chronic myelogenous leukemia(CML) patients. Ph chromosome results from a reciprocal translocation between the long arms of chromosomes 9 and 22,...
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Two Cases of Erythroleukemic Blast Crisis in Chronic Myelogenous Leukemia

Kim JY, Kim MS, Lim JH, Han KJ

  • KMID: 2089661
  • Korean J Clin Pathol.
  • 2001 Apr;21(2):93-97.
The erythroleukemic blast crisis in chronic myelogenous leukemia (CML) is rarely reported. We present two cases of erythroleukemic blast crisis of CML. In both cases, they had been treated with...
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A Case of Myeloid Blast Crisis of Ph-positive Chronic Myeloid Leukemia with t(3;21)(q26;q22)

Choi GJ, Chun HJ, Jeon DS, Kim JR, Kwon KY

  • KMID: 2039314
  • Korean J Clin Pathol.
  • 1997 Feb;17(1):21-27.
The t(3;21) (q26;q22) is associated with chronic myelogenous leukemia in blast crisis, leukemia evolving from therapy-related myelodysplasia, and with leukemia following other hematopoietic proliferative diseases. The t(3;21) is rare secondary...
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Erythroleukemic Blast Crisis of Chronic Myeloid Leukemia

Chung HJ, Chi HS, Seo EJ, Jang S, Park CJ, Lee KH

Erythroleukemic blast crisis of chronic myeloid leukemia (CML) is very rare. We report two cases of erythroleukemic blast crisis of CML resistant to imatinib treatment. Both patients made a rapid...
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Mutation of the N-ras Gene in a Patient Suffering from the Blast Phase of Chronic Myelogenous Leukemia

Song SH, Roh YW, Ahn YW, Kim YJ, Byoun YS, Choi JY, Hwang DW, Park BB, Choi JH, Kim IS, Kim BK, Lee YY

The blast phase in chronic myelogenous leukemia (CML) is associated with mutation of several genes. It is well known that p53 gene mutation plays a key role in the myeloid...
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Extramedullary B Lymphoblastic Crisis of CML, Presenting as a Leptomeningeal Tumor: A Case Report

Jeong H, Shin B, Bae SY, Lee S, Ryu Y, Kim H, Kim I

We report here on a rare case of a patient who presented with an extramedullary B lymphoblastic crisis as an initial manifestation of chronic myelogenous leukemia (CML). A 71-year-old man...
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Progressive De Novo DNA Methylation at the Pa Promotor of the Abl Genein the Bcr-Abl Locus during the Course of Chronic Myelogenous Leukemia

Yang SE, Chi HS

  • KMID: 2089552
  • Korean J Clin Pathol.
  • 1998 Sep;18(3):480-486.
BACKGROUND: In most cases of chronic myelogenous leukemia (CML), one of the two abl promotors (Pa) is nested within the bcr-abl hybrid gene and should be able to transcribe the...
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Tumor Lysis Syndrome in Lymphoblastic Crisis of CML

Lee DJ, Choi CU, Lee CS, Lee HH, Park JK, Choi JH, Lee YY, Kim IS

Tumor lysis syndrome (TLS) defines the metabolic derangements that occur with tumor breakdown following the initiation of cytotoxic therapy. TLS results from the rapid destruction of malignant cells and the...
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A Case of Gastric Extramedullary Tumor after Lymphoblastic Crisis in a Patient with Chronic Myelogenous Leukemia

Lee H, Lee JH, Kim JH, Choi SC, Park KW, Kim MH, Kim JJ, Rhee JC

  • KMID: 1572979
  • Korean J Gastrointest Endosc.
  • 2004 Feb;28(2):81-85.
A localized extramedullary tumor mass composed of immature cells has been reported in association with acute myeloid leukemia, myeloproliferative disorders, myelodysplasia in blast transformation or chronic myeloid leukemia with trilineage...
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A Case of Concomitant Inv(3)(q21q26) and Cryptic BCR/ABL1 Rearrangement in the Blast Crisis of Chronic Myeloid Leukemia

Lee H, Cho C, Kwon MJ, Nam MH, Lee CK, Kim YK

  • KMID: 2312184
  • Lab Med Online.
  • 2011 Jul;1(3):163-167.
Structural abnormalities of the long arm of chromosome 3 (3q) have been associated with elevated platelet count and hyperplasia of megakaryocytes with dysplasia in various hematological malignancies. Some cases of...
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Epidural Granulocytic Sarcoma involving the Thoracic Spine and Sternum in Acute Myelogenous Leukemia

Kim D, Oh D, Park S, Oh S, Kwon K, Lee Y, Kang M

  • KMID: 2083386
  • Korean J Hematol.
  • 1999 May;34(2):349-352.
Granulocytic sarcoma is a localized tumor composed of immature cells of the granulocytic series. Most granulocytic sarcomas occur in the course of acute leukemia and the blast crisis of chronic...
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ider (9) (q10)t (9;22) (q34;q11.2) as Secondary Karyotypic Aberration of Chronic Myelogeous Leukemia

Choi GJ, Jeon DS, Chun HJ, Kim JR, Song HS, Lee JW

  • KMID: 2225864
  • Korean J Clin Pathol.
  • 1999 Apr;19(2):266-270.
Although occasional patients with chronic myeloid leukemia (CML) have chromosomal changes other than Philadelphia chromosome early in the disease, in typical cases the 9;22 translocation remains the sole abnormality throughout...
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Clinical Implication of the Deletion Status of ABL-BCR on Derivative Chromosome 9 in Chronic Myelogenous Leukemia

Lee YK, Kim YR, Lee DS, She CJ, Yoon SS, Park SY, Kim BK, Cho HI

  • KMID: 2239626
  • Korean J Lab Med.
  • 2002 Dec;22(6):373-381.
BACKGROUND: The complementary ABL-BCR gene rearrangement is formed at chromosome 9 parallel to the Ph chromosome at der(22)t(9;22), which has been found deleted in a minority of chronic myelogenous leukemia...
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Clinical Resistance to the Tyrosine Kinase Inhibitor Imatinib (STI571) and Detection of BCR-ABL Gene Mutations in Korean Patients with Chronic Myeloid Leukemia

Sohn YH, Chi HS, Park CJ, Lee KH, Seo EJ

BACKGROUND: Imatinib mesylate, the tyrosine kinase activity of the BCR-ABL fusion gene, induces a remarkable remission in chronic myeloid leukemia (CML) patients. However, resistance to imatinib has been observed in...
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A Case of Granulocytic Sarcoma causing Spinal Cord Compression in Chronic Myelogenous Leukemia

Kim GT, Lee JH, Lee YH, Jeong SD, Jang MH, Kim HK, Ok JH, Kim BC

  • KMID: 2305235
  • Korean J Hematol.
  • 1998 Aug;33(2):268-272.
Granulocytic sarcoma is a localized tumor mass composed of immature cells of the granulocytic series. It can develope in patients with acute myelogenous leukemia or impending blast crisis of chronic...
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