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Oral Sumatriptan for Acute Treatment of Migraine A Single-blind Placebo-controlled Study

Jo KD, Lee MC

  • KMID: 2065977
  • J Korean Neurol Assoc.
  • 1995 Mar;13(1):77-83.
The efficacy and safety of oral sumatriptan as a 100mg conventional tablet was evaluated in the acute treatment of migrame in a single-blind, randomized, placebocontrolled, parallel-group study. Thirty patients were...
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A Case of Vasospastic Angina Pectoris Occurring Following Administration of Oral Imigran(R) for Migraine

Choi KH, Kim TY, Choi JH, Ok JW, Park JC, Oh J, Cho YK, Hwang KH, Lim SW, Cha DH

Imigran(R) (sumatriptan), a 5-hydroxytryptamine (HT) derivative, is highly effective in aborting attacks of migraine and cluster headache. The drug is generally well tolerated. However tolerated, although up to 8% of...
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Population pharmacokinetic analysis of the multiple peaks phenomenon in sumatriptan

Lee J, Lim MS, Seong SJ, Park SM, Gwon MR, Han S, Lee SM, Kim W, Yoon YR, Yoo HD

The objective of this study was to develop a population pharmacokinetic (PK) model for sumatriptan, which frequently shows an atypical absorption profile with multiple peaks. Sumatriptan, a selective agonist for...
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A Case of Cyclic Vomiting Syndrome Improved by Sumatriptan

Lee MH, Kim EJ, Chung IK, Kim HS, Park SH, Kim SJ

  • KMID: 1865902
  • Korean J Gastrointest Motil.
  • 1999 May;5(1):44-48.
Cyclic vomiting syndrome is a rare disorder characterized by recurrent, prolonged episodes of severe nausea and vomiting with no apparent cause. The vomiting is self-limited and patients have asymptomatic periods...
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The Clinical Efficacy of Subcutaneous Sumatriptan (Imigran) for Acute Treatment of Migraine

Joo JH, Lee SC, Sung SM, Jung DS, Park KH

  • KMID: 1957230
  • J Korean Neurol Assoc.
  • 1995 Sep;13(3):543-550.
Sumatripan is a selective agonist at the 5-hydroxytryptamine (5HT,) -like receptor. An open, uncontrolled study was conducted to evaluate the therapeutic response of Korean patients to sumatriptan 6mg using an...
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Determination of sumatriptan in human plasma using liquid chromatography-mass spectrometry for pharmacokinetic study in healthy Korean volunteers

Cho S, Jegal M, Ohk B, Kim BK, Gwon MR, Kang WY, Seong SJ, Kim HJ, Lee HW, Yoon YR

This study describes the development of an analytical method to determine sumatriptan levels in human plasma using high performance liquid chromatography (HPLC) coupled with triple quadrupole tandem mass spectrometry (MS/MS)...
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A Comparative Trial of Oral and Subcutaneous Sumatriptan in Acute Treatment of Migraine: a multicenter trial

Han SH, Huh K, Joo IS, Kim JI, Kim SM, Lee GH, Moon JS, Lee AY, Park HK, Shin HG

  • KMID: 2342719
  • J Korean Neurol Assoc.
  • 1998 Oct;16(5):644-653.
BACKGROUND: The efficacy of sumatriptan(SMN) in acute management of migrane has been well established. In Korea, however, a clinical study comparing the utility of oral(PO) and subcutaneous(SQ) regimen had not...
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Improvement of Migraine by Cervical Epidural Block: A case report

Kim KS, Lee WY, Woo SH, Hong KH

Migraine is a disabling headache that can occur with or without aura. We present here a case of migraine that was effectively managed by a series of cervical epidural blocks....
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Responses of Trigeminal Ganglion Neurons to Electrical and Mechanical Stimulation of the Middle Meningeal Artery, Superior Sagittal Sinus and Transverse Sinus in Rats

Lee KJ, Kim JW, Cho JK, Park HK, Park SC, Cho KK, Rha HK, Kang JK, Choi CR

  • KMID: 2044505
  • J Korean Neurosurg Soc.
  • 1999 Jun;28(6):752-761.
The intracranial blood vessels of the dura and the pia receive sensory afferent innervations from trigeminal nerve which has been believed to play a critical role in the mediation of...
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Cyclic Vomiting Syndrome: A Functional Disorder

Kaul A, Kaul KK

Cyclic vomiting syndrome (CVS) is a functional disorder characterized by stereotypical episodes of intense vomiting separated by weeks to months. Although it can occur at any age, the most common...
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