- A Hydroxyurea-induced Leg Ulcer
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Hwang SW, Hong SK, Kim SH, Seo JK, Lee D, Sung HS
- KMID: 2172063
- Ann Dermatol.
- 2009 Feb;21(1):39-41.
- doi: 10.5021/ad.2009.21.1.39
Hydroxyurea is a cytostatic agent that has recently become the drug of choice in the treatment of various myeloproliferative diseases. The cutaneous side effects of hydroxyurea include xerosis, hyperpigmentation, nail... -
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- Insights into the Transforming Growth Factor-beta Signaling Pathway in Cutaneous Melanoma
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Perrot CY, Javelaud D, Mauviel A
- KMID: 2171779
- Ann Dermatol.
- 2013 May;25(2):135-144.
- doi: 10.5021/ad.2013.25.2.135
Transforming growth factor-beta (TGF-beta) is a pleiotropic growth factor with broad tissue distribution that plays critical roles during embryonic development, normal tissue homeostasis, and cancer. While its cytostatic activity on... -
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- A comparative study of cytostatic intravesical instillation for superficial bladder tumor
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Ahn JS, Park YK
- KMID: 1913464
- Korean J Urol.
- 1992 Feb;33(1):58-64.
A total or 56 patients who underwent TUR-BT for superficial (stages O and A) bladder tumors received various chemoprophylactic treatment to prevent recurrence. 16 patients underwent resection only (Group I).... -
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- Radioprotective Effect of Mesna on Mouse Testis
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Ryu S, Kim JC, Kim SB, Park IK
- KMID: 1941517
- J Korean Soc Ther Radiol.
- 1990 Dec;8(2):145-150.
Mesna has been used with ifosfamide to prevent urotoxicity in the treatment of testicular cancers. This drug also protected the toxicities of adriamycin without compromising cytostatic activity. With n idea... -
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- Experimental study on the effect of surmin on penile squamous carcinoma cell line(CUPE-1)
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Kang IK, Moon WC
- KMID: 2289324
- Korean J Urol.
- 1993 Oct;34(5):748-763.
Experimental study was done to investigate the effect of suramin on the in vitro and in vivo proliferation and metastasis of penile squamous carcinoma cell line(CUPE-1), morphological changes of CUPE-1... -
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- Anti-tumor activity of tumor necrosis factor alone and combination with VP-16 on renal cell carcinoma in a nude mice xenograft model
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Myong SC, Moon WC, Kim YS
- KMID: 2289385
- Korean J Urol.
- 1992 Dec;33(6):954-960.
Investigations of the anti-tumor activity of recombinant mouse TNF and etoposide(VP-16) in a nude mouse subcutaneous implantation xenograft model utilizing the CURC-1 human renal cell carcinoma cell line were performed.... -
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- Hand-Foot syndrome induced by sorafenib, a multitargeted tyrosine kinase inhibitor, in a patient with advanced renal cell carcinoma
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Lee SH, Noh SH, Kim SY, Jang KY, Hwang PH
- KMID: 2037347
- Korean J Pediatr.
- 2009 Jan;52(1):119-123.
- doi: 10.3345/kjp.2009.52.1.119
Renal cell carcinoma (RCC) arising from epithelial cells of the renal tubules is a highly aggressive and malignant tumor in all ages; however, it rarely occurs in children. the standard... -
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- Expression of Cyclin D1, Cyclin E, p21Cip1 and p27Kip1 in Chemically Induced Rat Mammary Tumor Treated with Tamoxifen and Transforming Growth Factor-1
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Jang TJ, Park JH, Cho MY, Kim KK, Kim JR
- KMID: 2275646
- Korean J Pathol.
- 2001 Apr;35(2):151-157.
BACKGROUND: Tamoxifen (TAM) inhibits the action of estrogen by binding to estrogen receptors, and also has non-estrogen receptor mediated cytostatic activities. Transforming growth factor-1 (TGF-1) inhibits the proliferation of many... -
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- Effects of BCG or CP-2 on the DNA Synthesis in the Epithelial Cells of the Mouse Appendix
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Jung WH, Ahn ET, Park KH, Park DK, Kim MS, Ko JS
- KMID: 2092876
- Korean J Anat.
- 2006 Oct;39(5):343-351.
This experiment was performed to evaluate the morphological responses of the appendicular mucosa of the mouse, inoculated with Ehrlich carcinoma cells in the inguinal area, following administration of BCG or... -
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- Effects of New Nultidrug - Resistance Reversing Agent, KR-30035, on Tumoral Uptake of Tc-99m MIBI In-vitro and In-vivo
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Cho IH, Lee J, Suh JS, Lee BH, Choi SW, Sohn SK, Lee CO, Yoo SE, Chung JK, Lee KB
- KMID: 2329172
- J Korean Cancer Assoc.
- 1999 Aug;31(4):773-783.
PURPOSE: Verapamil is one of the most extensively characterized modulators of P-glyco- protein (P-gp) mediated multi-drug resistance (MDR), but its plasma concentration required to reverse MDR can cause cardiovascular toxicity.... -
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- Effects of REtinoic Acid and Radiation on the Growth of Cell Lines of Human Head and Neck Squamous Cell Carcinoma
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Seo JH, Yoo YA, Choi IK, Kim SJ, Choi CW, Kim BS, Kim CY, Shin SW, Kim YH, Choi MS, Kim JS
- KMID: 2006871
- J Korean Cancer Assoc.
- 1998 Aug;30(4):772-780.
PURPOSE: Mammalian tumor cells differ in their response to ionizing radiation to a degree that some patients are readily curable with conventional doses of radiation, while others are rarely controlled.... -
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- Preclinical Efficacy of [Vâ´Qâµ]dDAVP, a Second Generation Vasopressin Analog, on Metastatic Spread and Tumor-Associated Angiogenesis in Colorectal Cancer
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Garona J, Sobol NT, Pifano M, Segatori V, Gomez DE, Ripoll GV, Alonso DF
- KMID: 2464391
- Cancer Res Treat.
- 2019 Apr;51(2):438-450.
- doi: 10.4143/crt.2018.040
PURPOSE: Control of metastatic spread of colorectal cancer (CRC) remains as a major therapeutic challenge. [V4 Q5 ]dDAVP is a vasopressin peptide analog with previously reported anticancer activity against carcinoma... -
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- Effects of Acriflavine-Guanosine Composition (AG60) on the DNA Synthesis and Ultrastructure of Epithelial Cells of the Appendix of Mice Inoculated with Ehrlich Carcinoma Cells
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Choi PC, Ahn ET, Park KH, Park DK, Ko JS
- KMID: 2092877
- Korean J Anat.
- 2006 Oct;39(5):353-365.
This experiment was performed to evaluate the morphological responses of the mucosa of the mouse appendix, inoculated with Ehrlich carcinoma cells in the inguinal area, following administration of Acriflavine-Guanosine Composition... -
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- Antitumor Activity of Oxaliplatin, 5-FU and Paclitaxel Given Alone or in Combination with ZD1839 in Human Gastric Carcinoma Cells in vitro
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Jang JH, Lee SH, Kang JH, Sun HS, Nishio K, Saijo N, Kuh HJ
- KMID: 1972943
- Cancer Res Treat.
- 2002 Oct;34(5):372-381.
PURPOSE: Oxaliplatin (LOHP), 5-FU, and paclitaxel (PTX) are considered highly active against advanced gastric carcinomas, and the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, ZD1839 is considered as a... -
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- Anti-tumor Effects of Growth Factor Inhibitors and Anti-metastatic Agents in Human Gastric Cancer Cell Lines
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Rha SY, Chung HC, Gong SJ, Chung HC, Kim JH, Roh JK, Min JS, Kim BS
- KMID: 1906170
- J Korean Cancer Assoc.
- 1997 Jun;29(3):391-403.
PURPOSE: For tumor growth, invasion and metastasis, a cascade of linked sequential biological events is essential; overproduction of growth factors, activation of proteolytic enzymes, induction of tumor angiogenesis, and enhanced... -
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- Anticancer Effect of AG60 (Acriflavine-Guanosine Compound) on the Ehrlich Cancer Cells Light Microscopic, Autoradiographic and Electron Microscopic Study
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Ahn ET, Ko JS, Kim HJ, Kim SG, Lee KY, Kang JK, Yoo BI, Chung YS, Hong EK, Han YB
- KMID: 2224573
- Korean J Anat.
- 1999 Apr;32(2):117-134.
To evaluate the effect and working mechanism of a newly developed anti-cancer drug, AG60 (acriflavine-guanosine compound, Taerim Pharm. Co. Seoul, Korea), histotologic, autoradiographic and electron microscopic studies were carried out.... -
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