- Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis
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Lim S, Han A, Kim D, Seo HS
- KMID: 2068735
- J Bacteriol Virol.
- 2015 Sep;45(3):200-214.
- doi: 10.4167/jbv.2015.45.3.200
Salmonella causes a wide variety of diseases ranging from mild diarrhea to severe systemic infections, such as like typhoid fever, in multiple organisms, ranging from mice to humans. A lack... -
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- Sargassum coreanum extract alleviates hyperglycemia and improves insulin resistance in db/db diabetic mice
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Park MH, Nam YH, Han JS
- KMID: 2313867
- Nutr Res Pract.
- 2015 Oct;9(5):472-479.
- doi: 10.4162/nrp.2015.9.5.472
BACKGROUND/OBJECTIVES: The goal of this study was to examine the effect of Sargassum coreanum extract (SCE) on blood glucose concentration and insulin resistance in C57BL-KsJ-db/db mice. MATERIALS/METHODS: For 6 weeks, male... -
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- Gynura procumbens extract improves insulin sensitivity and suppresses hepatic gluconeogenesis in C57BL/KsJ-db/db mice
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Choi SI, Lee HA, Han JS
- KMID: 2434085
- Nutr Res Pract.
- 2016 Oct;10(5):507-515.
- doi: 10.4162/nrp.2016.10.5.507
BACKGROUND/OBJECTIVES: This study was designed to investigate whether Gynura procumbens extract (GPE) can improve insulin sensitivity and suppress hepatic glucose production in an animal model of type 2 diabetes. MATERIALS/METHODS: C57BL/Ksj-db/db... -
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- D-Xylose as a sugar complement regulates blood glucose levels by suppressing phosphoenolpyruvate carboxylase (PEPCK) in streptozotocin-nicotinamide-induced diabetic rats and by enhancing glucose uptake in vitro
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Kim E, Kim YS, Kim KM, Jung S, Yoo SH, Kim Y
- KMID: 2313895
- Nutr Res Pract.
- 2016 Feb;10(1):11-18.
- doi: 10.4162/nrp.2016.10.1.11
BACKGROUND/OBJECTIVES: Type 2 diabetes (T2D) is more frequently diagnosed and is characterized by hyperglycemia and insulin resistance. D-Xylose, a sucrase inhibitor, may be useful as a functional sugar complement to... -
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- Virulence genes of Streptococcus mutans and dental caries
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You YO
- KMID: 2452744
- Int J Oral Biol.
- 2019 Jun;44(2):31-36.
- doi: 10.11620/IJOB.2019.44.2.31
Streptococcus mutans is one of the important bacteria that forms dental biofilm and cause dental caries. Virulence genes in S. mutans can be classified into the genes involved in bacterial... -
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- Identification of Hypoxanthine and Phosphoenolpyruvic Acid as Serum Markers of Chemoradiotherapy Response in Locally Advanced Rectal Cancer
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Kim K, Yeo SG, Yoo BC
- KMID: 2380393
- Cancer Res Treat.
- 2015 Jan;47(1):78-89.
- doi: 10.4143/crt.2013.127
PURPOSE: Patients show variable responses to chemoradiotherapy (CRT), which is generally administered before surgery for locally advanced rectal cancer (LARC). The aim of this study was to identify molecular markers... -
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- 4-hydroxy-3-methoxycinnamic acid regulates orexigenic peptides and hepatic glucose homeostasis through phosphorylation of FoxO1
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Kinyua AW, Ko CM, Doan KV, Yang DJ, Huynh MK, Moh SH, Choi YH, Kim KW
- KMID: 2440019
- Exp Mol Med.
- 2018 Feb;50(2):e437.
- doi: 10.1038/emm.2017.253
4-hydroxy-3-methoxycinnamic acid (ferulic acid, FA) is known to have numerous beneficial health effects, including anti-obesity and anti-hyperglycemic properties. However, the molecular networks that modulate the beneficial FA-induced metabolic effects have... -
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- Picroside II attenuates fatty acid accumulation in HepG2 cells via modulation of fatty acid uptake and synthesis
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Dhami-Shah H, Vaidya R, Udipi S, Raghavan S, Abhijit S, Mohan V, Balasubramanyam M, Vaidya A
- KMID: 2429085
- Clin Mol Hepatol.
- 2018 Mar;24(1):77-87.
- doi: 10.3350/cmh.2017.0039
BACKGROUND/AIMS: Hepatic steatosis is caused by an imbalance between free fatty acids (FFAs) uptake, utilization, storage, and disposal. Understanding the molecular mechanisms involved in FFAs accumulation and its modulation could... -
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- Anti-hyperglycemic effects and signaling mechanism of Perilla frutescens sprout extract
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Kim DH, Kim SJ, Yu KY, Jeong SI, Kim SY
- KMID: 2429015
- Nutr Res Pract.
- 2018 Feb;12(1):20-28.
- doi: 10.4162/nrp.2018.12.1.20
BACKGROUND/OBJECTIVES: Perilla frutescens (L.) Britton var. (PF) sprout is a plant of the labiate family. We have previously reported the protective effects of PF sprout extract on cytokine-induced β-cell damage.... -
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- Telmisartan increases hepatic glucose production via protein kinase C ζ-dependent insulin receptor substrate-1 phosphorylation in HepG2 cells and mouse liver
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Cho KW, Cho DH
- KMID: 2434096
- Yeungnam Univ J Med.
- 2019 Jan;36(1):26-35.
- doi: 10.12701/yujm.2019.00059
BACKGROUND: Dysregulation of hepatic glucose production (HGP) contributes to the development of type 2 diabetes mellitus. Telmisartan, an angiotensin II type 1 receptor blocker (ARB), has various ancillary effects in... -
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- Overexpression of Neuron-Specific Enolase as a Prognostic Factor in Patients with Gastric Cancer
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Park T, Lee YJ, Jeong SH, Choi SK, Jung EJ, Ju YT, Jeong CY, Park M, Hah YS, Yoo J, Ha WS, Hong SC, Ko GH
- KMID: 2389827
- J Gastric Cancer.
- 2017 Sep;17(3):228-236.
- doi: 10.5230/jgc.2017.17.e28
PURPOSE: Enolase is a cytoplasmic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. The aim of this study was to investigate whether the overexpression of... -
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- Increased glucose metabolism and alpha-glucosidase inhibition in Cordyceps militaris water extract-treated HepG2 cells
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Kim DJ, Kang YH, Kim KK, Kim TW, Park JB, Choe M
- KMID: 2407765
- Nutr Res Pract.
- 2017 Jun;11(3):180-189.
- doi: 10.4162/nrp.2017.11.3.180
BACKGROUND/OBJECTIVES: Recent living condition improvements, changes in dietary habits, and reductions in physical activity are contributing to an increase in metabolic syndrome symptoms including diabetes and obesity. Through such societal... -
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- Anti-diabetic effect of purple corn extract on C57BL/KsJ db/db mice
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Huang B, Wang Z, Park JH, Ryu OH, Choi MK, Lee JY, Kang YH, Lim SS
- KMID: 2313805
- Nutr Res Pract.
- 2015 Feb;9(1):22-29.
- doi: 10.4162/nrp.2015.9.1.22
BACKGROUND/OBJECTIVES: Recently, anthocyanins have been reported to have various biological activities. Furthermore, anthocyanin-rich purple corn extract (PCE) ameliorated insulin resistance and reduced diabetes-associated mesanginal fibrosis and inflammation, suggesting that it... -
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