- Antifungal Effects of Bee Venom Components on Trichophyton rubrum: A Novel Approach of Bee Venom Study for Possible Emerging Antifungal Agent
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Park J, Kwon O, An HJ, Park KK
- KMID: 2414682
- Ann Dermatol.
- 2018 Apr;30(2):202-210.
- doi: 10.5021/ad.2018.30.2.202
BACKGROUND: Bee venom (BV) has been widely investigated for potential medical uses. Recent inadvertent uses of BV based products have shown to mitigate signs of fungal infections. However, the component... -
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- Rhabdomyolysis and Acute Renal Failure Due to Honeybee Stings
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Cho YM, Rhew MH, Chin HJ, Lim CS, Ahn CR, Han JS, Kim SG, Lee JS
- KMID: 2307370
- Korean J Nephrol.
- 1998 Jan;17(1):166-169.
Honeybee venom consists of melittin, apamin, phospholipase A2, hyaluronidase and other biologically active substances. It can cause potentially lethal reaction after mass envenomation. But, acute renal failure following multiple bee... -
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- Evaluation of Antifungal Activities of Bee Venom Components Against Malassezia Strains
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Kim JH, Park J, Park KK, An HJ, Lee YW
- KMID: 2470573
- Korean J Med Mycol.
- 2019 Dec;24(4):91-95.
- doi: 10.17966/JMI.2019.24.4.91
BACKGROUND: Several studies about bee venom components have reported anti-fungal, anti-inflammatory, and anti-cancer effects. Malassezia species are components of skin flora, and also associated with many dermatologic diseases such as... -
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- Multiple 5-Hydroxytryptamine (5-HT) Receptors Are Involved in the Melittin-induced Nociceptive Responses in Rat I. Role of Peripheral 5-HT Receptor
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Shin HK, Lee SE
- KMID: 2285346
- Korean J Physiol Pharmacol.
- 2007 Oct;11(5):221-226.
Melittin-induced tonic pain model is characterized by local inflammation, edema, spontaneous flinchings, and sustained mechanical hypersensitivity. These nociceptive responses are mediated through selective activation of capsaicin-sensitive primary afferent fibers by... -
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- Mediation of intracellular Ca2+ in the phospholipase A2-induced cell proliferation in human neuroblastoma cells
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Kim JA, Lee YS
- KMID: 2285203
- Korean J Physiol Pharmacol.
- 1998 Aug;2(4):411-417.
The role of phospholipase A2 (PLA2) in tumor cell growth was investigated using SK-N-MC human neuroblastoma cells. 4-Bromophenacyl bromide (BPB) and mepacrine (Mep), known PLA2 inhibitors, suppressed growth of the tumor cells in... -
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- Melittin Ameliorates the Inflammation of Organs in an Amyotrophic Lateral Sclerosis Animal Model
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Lee SH, Choi SM, Yang EJ
- KMID: 2009028
- Exp Neurobiol.
- 2014 Mar;23(1):86-92.
- doi: 10.5607/en.2014.23.1.86
Amyotrophic lateral sclerosis (ALS) is a devastating progressive neurodegenerative disorder characterized by a selective loss of motor neurons in the spinal cord, brainstem, and motor cortex, leading to weakness of... -
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- Melittin-induced Nociceptive Responses are Alleviated by Cyclooxygenase-1 Inhibitor
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Kim J, Shin HK, Lee KH
- KMID: 1512941
- Korean J Physiol Pharmacol.
- 2006 Feb;10(1):45-50.
Melittin-induced pain model has been known to be very useful for the study of pain mechanism. Melittin-induced nociceptive responses are reported to be modulated by the changes in the activity... -
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- Spinal Metabotropic Glutamate Receptors (mGluRs) are Involved in the Melittin-induced Nociception in Rats
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Cho CH, Shin HK
- KMID: 1486105
- Korean J Physiol Pharmacol.
- 2008 Oct;12(5):237-243.
- doi: 10.4196/kjpp.2008.12.5.237
Intraplantar injection of melittin has been known to induce sustained decrease of mechanical threshold and increase of spontaneous flinchings. The present study was undertaken to investigate how the melittin-induced nociceptive... -
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- Calcium Ions are Involved in Modulation of Melittin-induced Nociception in Rat: II. Effect of Calcium Chelator
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Shin HK, Lee KH, Cho CH
- KMID: 1587466
- Korean J Physiol Pharmacol.
- 2006 Dec;10(6):297-302.
Melittin, a major component of bee venom, produces a sustained decrease in mechanical threshold, and an increase in spontaneous flinchings and paw thickness, which are characteristics similar to those induced... -
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- Efficacy of Bee Venom Injection for Osteoarthritis Patients
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Won CH, Choi ES, Hong SS
- KMID: 2101996
- J Korean Rheum Assoc.
- 1999 Sep;6(3):218-226.
OBJECTIVES: Bee venom contains a potent antiinflammatory peptide 401 as well as mellitin. The purpose of this study was to see the efficacy and safety of purified bee venom injection... -
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- Intracellular Ca2+ Mobilization and Beta-hexosaminidase Release Are Not Influenced by 60 Hz-electromagnetic Fields (EMF) in RBL 2H3 Cells
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Hwang YH, Song HS, Kim HR, Ko MS, Jeong JM, Kim YH, Ryu JS, Sohn UD, Gimm YM, Myung SH, Sim SS
- KMID: 2071735
- Korean J Physiol Pharmacol.
- 2011 Oct;15(5):313-317.
- doi: 10.4196/kjpp.2011.15.5.313
The effects of extremely low frequency electromagnetic fields (EMF) on intracellular Ca2+ mobilization and cellular function in RBL 2H3 cells were investigated. Exposure to EMF (60 Hz, 0.1 or 1... -
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- The Effect of Caffeic Acid on Wound Healing in Skin-incised Mice
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Song HS, Park TW, Sohn UD, Shin YK, Choi BC, Kim CJ, Sim SS
- KMID: 2285362
- Korean J Physiol Pharmacol.
- 2008 Dec;12(6):343-347.
- doi: 10.4196/kjpp.2008.12.6.343
This study was carried out to investigate the wound healing effect of caffeic acid in skin-incised mice. Caffeic acid showed significant effects on anti-inflammatory activity and wound healing, such as... -
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- Comparative Study on the Nociceptive Responses Induced by Whole Bee Venom and Melittin
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Shin HK, Lee KH, Lee SE
- KMID: 1611432
- Korean J Physiol Pharmacol.
- 2004 Oct;8(5):281-288.
The present study was undertaken to confirm whether melittin, a major constituent of whole bee venom (WBV), had the ability to produce the same nociceptive responses as those induced by... -
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- Calcium Ions are Involved in Modulation of Melittin-induced Nociception in Rat: I. Effect of Voltage-gated Calcium Channel Antagonist
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Shin HK, Le KH
- KMID: 2071634
- Korean J Physiol Pharmacol.
- 2006 Oct;10(5):255-261.
Melittin-induced nociceptive responses are mediated by selective activation of capsaicin-sensitive primary afferent fibers and are modulated by excitatory amino acid receptor, cyclooxygenase, protein kinase C and serotonin receptor. The present... -
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- N-methyl-D-aspartate (NMDA) and Non-NMDA Receptors are Involved in the Production and Maintenance of Nociceptive Responses by Intraplantar Injection of Bee Venom and Melittin in the Rat
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Kim JH, Shin HK
- KMID: 1600061
- Korean J Physiol Pharmacol.
- 2005 Jun;9(3):179-186.
Whole bee venom (WBV) and its major component, melittin, have been reported to induce long-lasting spontaneous flinchings and hyperalgesia. The current study was designed to elucidate the peripheral and spinal... -
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