- The Role of Macrophage Lipophagy in Reverse Cholesterol Transport
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Jeong SJ, Lee MN, Oh GT
- KMID: 2413285
- Endocrinol Metab.
- 2017 Mar;32(1):41-46.
- doi: 10.3803/EnM.2017.32.1.41
Macrophage cholesterol efflux is a central step in reverse cholesterol transport, which helps to maintain cholesterol homeostasis and to reduce atherosclerosis. Lipophagy has recently been identified as a new step... -
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- Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3
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Park YK, Jang BC
- KMID: 2469571
- Keimyung Med J.
- 2019 Dec;38(1,2):1-10.
- doi: 10.0000/kmj.2019.38.1.1
Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of... -
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- Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3
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Park YK, Jang BC
- KMID: 2469552
- Keimyung Med J.
- 2019 Dec;38(1-2):1-10.
- doi: 10.0000/kmj.2019.38.1.1
Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of... -
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- Cryptotanshinone Inhibits Lipid Accumulation in Differentiating 3T3-L1 Preadipocytes by Down-regulating C/EBP-α, PPAR-γ, FAS, Perilipin A, and STAT-3
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Park YK, Jang BC
- KMID: 2469544
- Keimyung Med J.
- 2019 Dec;38(1):1-10.
- doi: 10.0000/kmj.2019.38.1.1
Differentiation of preadipocyte, also named adipogenesis, leads to the phenotype of mature adipocyte that is filled with many lipid droplets. Excessive lipid accumulation in adipocytes leads to the development of... -
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- Effect of Fibroblast Growth Factor-2 and Retinoic Acid on Lineage Commitment of Bone Marrow Mesenchymal Stem Cells
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Lim J, Park EK
- KMID: 2360866
- Tissue Eng Regen Med.
- 2016 Feb;13(1):47-56.
- doi: 10.1007/s13770-016-9102-0
In this study, we examined the effect of a combination of fibroblast growth factor-2 (FGF-2) and retinoic acid (RA) on osteoblast and adipocyte lineage commitment and differentiation of human bone... -
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- Ultrastructural Changes in Skeletal Muscle of Infants with Mitochondrial Respiratory Chain Complex I Defects
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Mun JY, Jung MK, Kim SH, Eom S, Han SS, Lee YM
- KMID: 2392131
- J Clin Neurol.
- 2017 Oct;13(4):359-365.
- doi: 10.3988/jcn.2017.13.4.359
BACKGROUND AND PURPOSE: The pathogenesis of mitochondrial disease (MD) involves the disruption of cellular energy metabolism, which results from defects in the mitochondrial respiratory chain complex (MRC). We investigated whether... -
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- Inhibition of ER Stress by 2-Aminopurine Treatment Modulates Cardiomyopathy in a Murine Chronic Chagas Disease Model
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Ayyappan J, lizardo K, Wang S, Yurkow E, Nagajyothi JF
- KMID: 2455094
- Biomol Ther.
- 2019 Jul;27(4):386-394.
- doi: 10.4062/biomolther.2018.193
Trypanosoma cruzi infection results in debilitating cardiomyopathy, which is a major cause of mortality and morbidity in the endemic regions of Chagas disease (CD). The pathogenesis of Chagasic cardiomyopathy (CCM)... -
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- Effects of Lonicera caerulea extract on adipocyte differentiation and adipogenesis in 3T3-L1 cells and mouse adipose-derived stem cells (MADSCs)
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Park M, Lee C, Lee HJ
- KMID: 2466679
- J Nutr Health.
- 2019 Feb;52(1):17-25.
- doi: 10.4163/jnh.2019.52.1.17
PURPOSE: Obesity is a major health problem of global significance because it is clearly associated with an increased risk of health problems, such as nonalcoholic fatty liver disease (NAFLD), diabetes,... -
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- TonEBP suppresses adipocyte differentiation via modulation of early signaling in 3T3-L1 cells
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Kim SJ, Kim T, Choi HN, Cho EJ, Park JB, Jeon BH, Lee SD
- KMID: 2364269
- Korean J Physiol Pharmacol.
- 2016 Nov;20(6):649-655.
- doi: 10.4196/kjpp.2016.20.6.649
TonEBP belongs to the Rel family of transcription factors and plays important roles in inflammation as well as kidney homeostasis. Recent studies suggest that TonEBP expression is also involved in... -
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- Ultrastructural changes of fat-storing cells in experimental hepatic fibrosis
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Kim MJ, Choi WH, Lee TS
- KMID: 2377578
- Yeungnam Univ J Med.
- 1992 Dec;9(2):224-238.
- doi: 10.12701/yujm.1992.9.2.224
Hepatic fibrosis was induced in Sprague-Dawley rate to evaluate the ultrastructural changes of fat-storing cells (Ito cells). For experimental induction of liver fibrosis, the rats were administered intraperitoneally with 0.5... -
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- The effects of Brassica juncea L. leaf extract on obesity and lipid profiles of rats fed a high-fat/high-cholesterol diet
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Lee JJ, Kim HA, Lee J
- KMID: 2420995
- Nutr Res Pract.
- 2018 Aug;12(4):298-306.
- doi: 10.4162/nrp.2018.12.4.298
BACKGROUND/OBJECTIVES: Obesity is a global health problem of significant importance which increases mortality. In place of anti-obesity drugs, natural products are being developed as alternative therapeutic materials. In this study,... -
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- Zaluzanin C Inhibits Differentiation of 3T3-L1 Preadipocytes into Mature Adipocytes
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Kwak SH, Kim YH
- KMID: 2459822
- J Obes Metab Syndr.
- 2019 Jun;28(2):105-111.
- doi: 10.7570/jomes.2019.28.2.105
BACKGROUND: An excess storage of body fat causes obesity. Since obesity increases risk of chronic diseases, it is important to inhibit excessive storage of fat. Zaluzanin C is a sesquiterpene... -
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- Protective effects of Cirsium setidens ethanolic extracts against alcoholic fatty liver injury in rats
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Kim EH, Chung J
- KMID: 2366713
- J Nutr Health.
- 2016 Dec;49(6):420-428.
- doi: 10.4163/jnh.2016.49.6.420
PURPOSE: In this study, we investigated the effects of Cirsium setidens ethanolic extract (CS) on the development of alcoholic fatty liver and associated injury. METHODS: Sprague-Dawley male rats were fed either... -
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- LC/MS-based Analysis of Bioactive Compounds from the Bark of Betula platyphylla var. japonica and Their Effects on Regulation of Adipocyte and Osteoblast Differentiation
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Baek SC, Choi E, Eom HJ, Jo MS, Kim S, So HM, Kim SH, Kang KS, Kim KH
- KMID: 2432417
- Nat Prod Sci.
- 2018 Dec;24(4):235-240.
- doi: 10.20307/nps.2018.24.4.235
Betula platyphylla var. japonica (Betulaceae), also known as Asian white birch, is an endemic medicinal tree, the bark of which has been used in Chinese traditional medicine for the treatment... -
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- Morphological Characteristics of Residual Skin Surface Components Collected from the Surface of Facial Skin in Women of Different Age
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Chalyk NE, Bandaletova TY, Kyle NH, Petyaev IM
- KMID: 2388944
- Ann Dermatol.
- 2017 Aug;29(4):454-461.
- doi: 10.5021/ad.2017.29.4.454
BACKGROUND: Problems of skin aging and its prevention currently attract increasing attention with the growth of human life expectancy. The morphology of the stratum corneum (SC) is well known, but... -
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- Intracellular Remodeling and Accumulation of Aberrant Lysosomes in Differentiation of Tonsil-Derived Mesenchymal Stem Cells into Parathyroid-Like Cells
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Jo YI, Kim G, Jin YM, Park YJ, Kim HS, Park YS
- KMID: 2394975
- Tissue Eng Regen Med.
- 2017 Aug;14(4):411-420.
- doi: 10.1007/s13770-017-0042-5
Differentiation of mesenchymal stem cells (MSC) into a variety of cell lineages such as adipocytes, osteocytes, and chondrocytes is often accompanied up-regulation of autophagy. In our study, we demonstrated that... -
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- Ultrastructure of Articular Cartilage in Immobilized Knee Joints of Rabbits
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Jahng JS
- KMID: 2471506
- J Korean Orthop Assoc.
- 1974 Jun;9(2):221-229.
- doi: 10.4055/jkoa.1974.9.2.221
Mature articular cartilage is an aneural, avascular, and alymphatic specialized form of connective tissue, and it has been emphasized that destruction of articular cartilage is the starting point in the... -
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- Olmsted Syndrome Caused by a Heterozygous p.Gly568Val Missense Mutation in TRPV3 Gene
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Choi JY, Kim SE, Lee SE, Kim SC
- KMID: 2418801
- Yonsei Med J.
- 2018 Mar;59(2):341-344.
- doi: 10.3349/ymj.2018.59.2.341
Olmsted syndrome (OS) is a rare congenital skin disorder characterized by severe palmoplantar and periorificial keratoderma, alopecia, onychodystrophy, and severe pruritus. Recently, pathogenic ‘gain-of-function‘ mutations of the transient receptor potential... -
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- Correlation of spontaneous adipocyte generation with osteogenic differentiation of porcine skin-derived stem cells
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Bae HK, Jung BD, Lee S, Park CK, Yang BK, Cheong HT
- KMID: 2434773
- J Vet Sci.
- 2019 Jan;20(1):16-26.
- doi: 10.4142/jvs.2019.20.1.16
The objective of this study was to examine effects of spontaneous adipocyte generation on osteogenic differentiation of porcine skin-derived stem cells (pSSCs). Correlation between osteogenic differentiation and adipocyte differentiation induced... -
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- Anti-diabetic effects of blue honeyberry on high-fed-diet-induced type II diabetic mouse
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Sharma A, Kim JW, Ku SK, Choi JS, Lee HJ
- KMID: 2464115
- Nutr Res Pract.
- 2019 Oct;13(5):367-376.
- doi: 10.4162/nrp.2019.13.5.367
BACKGROUND/OBJECTIVE: The blue honeysuckle berry (Lonicera caerulea var. edulis L.) is a small deciduous shrub belonging to the Caprifoliaceae family that is native to Russia, China, Japan, and Korea. The... -
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