KoreaMed

Probiotic products in various formulations are widely used world-wide for a seemingly limitless range of indications––from health maintenance to the alleviation of common intestinal ailments and on to the prevention...

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9 Yokukansan Suppresses Gastric Hypersensitivity and Eosinophil-associated Microinflammation in Rats With Functional Dyspepsia

Duan S, Imamura N, Kondo T, Kanda H, Kogure Y, Okugawa T, Fukushima M, Tomita T, Oshima T, Fukui H, Noguchi K, Dai Y, Miwa H

KMID: 2528040
J Neurogastroenterol Motil.
2022 Apr;28(2):255-264.
doi: 10.5056/jnm21204

Background/Aims Herbal medicine is an important complementary therapy for functional dyspepsia (FD). However, its effect against gastric hypersensitivity in patients with FD has rarely been evaluated. Yokukansan (YKS), a traditional Japanese...

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10 Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea

Lee JY, Lim CH, Kim DH, Jung HY, Youn YH, Jung DH, Park JC, Moon HS, Hong SJ, Therapeutic Endoscopy and Instrument for Functional Gastrointestinal Disorders Study Group Under the Korean Society of Neurogastroenterology and Motility

KMID: 2528039
J Neurogastroenterol Motil.
2022 Apr;28(2):247-254.
doi: 10.5056/jnm21081

Background/Aims To analyze various adverse events (AEs) related to the peroral endoscopic myotomy (POEM) procedure and to analyze whether these AEs are related to an extended hospital stay. Methods Patients admitted for POEM...

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11 Effect of Drinking Warm Water on Esophageal Preparation Before Peroral Endoscopic Myotomy in Patients With Achalasia

Yoon HJ, Youn YH, Yoo SH, Jeon S, Park H

KMID: 2528037
J Neurogastroenterol Motil.
2022 Apr;28(2):231-236.
doi: 10.5056/jnm21119

Background/Aims Food retention, which is a characteristic observed in patients with achalasia, can interfere with peroral endoscopic myotomy (POEM). However, there is no established guideline for esophageal preparation for POEM. A previous...

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12 Overlap Between Constipation and Gastroesophageal Reflux Disease in Japan: Results From an Internet Survey

Ogasawara N, Funaki Y, Kasugai K, Ebi M, Tamura Y, Izawa S, Sasaki M

KMID: 2528044
J Neurogastroenterol Motil.
2022 Apr;28(2):291-302.
doi: 10.5056/jnm21065

Background/Aims Detailed evaluations of overlapping constipation and gastroesophageal reflux disease (GERD) have not been conducted in Japan. The REACTION-J2 study examined the overlap of these diseases in Japan. Methods This internet-based survey recruited...

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13 Three-dimensional High-resolution Anorectal Manometry in Children With Non-retentive Fecal Incontinence

Banasiuk M, Dziekiewicz M, Dobrowolska M, Skowrońska B, Dembiński Ł, Banaszkiewicz A

KMID: 2528045
J Neurogastroenterol Motil.
2022 Apr;28(2):303-311.
doi: 10.5056/jnm20216

Background/Aims Three-dimensional high-resolution anorectal manometry (3D-HRAM) is a precise tool to assess the function of the anorectum. Our aim is to evaluate children diagnosed with non-retentive fecal incontinence (NRFI) using 3D-HRAM. Methods In...

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14 Association Between Psychosocial Disorders and Gastroesophageal Reflux Disease: A Systematic Review and Meta-analysis

He M, Wang Q, Yao D, Li J, Bai G

KMID: 2528035
J Neurogastroenterol Motil.
2022 Apr;28(2):212-221.
doi: 10.5056/jnm21044

Background/Aims The incidence of gastroesophageal reflux disease (GERD) is increasing annually. Studies have suggested that psychosocial disorders may be linked to the development of GERD. However, studies evaluating the association between...

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15 Transanal Irrigation for Neurogenic Bowel Dysfunction in Multiple Sclerosis: A Retrospective Study

Teng M, Miget G, Moutounaïck M, Kervinio F, Charlanes A, Chesnel C, Breton FL, Amarenco G

KMID: 2528047
J Neurogastroenterol Motil.
2022 Apr;28(2):320-326.
doi: 10.5056/jnm19040

Background/Aims Sixty-eight percent of multiple sclerosis (MS) patients suffer from neurogenic bowel dysfunction (NBD). Transanal irrigation (TAI) is part of the therapeutic strategy. This retrospective study aims to assess the efficacy...

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16 A Randomized, Double-blinded, Placebocontrolled Study to Evaluate the Efficacy and Safety of DA-9701 (Motilitone) in Patients With Constipation-type Irritable Bowel Syndrome and Functional Dyspepsia Overlap: A Pilot Study

Lee JY, Kim N, Yoon H, Shin CM, Park YS, Lee DH

KMID: 2528041
J Neurogastroenterol Motil.
2022 Apr;28(2):265-275.
doi: 10.5056/jnm20236

Background/Aims To assess the effects and safety of DA-9701 (Motilitone) in patients with constipation-type irritable bowel syndrome (IBS-C) which frequently accompany functional dyspepsia (FD). Methods FD and IBS-C were diagnosed based on the Rome...

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17 Pathophysiological Commonality Between Irritable Bowel Syndrome and Metabolic Syndrome: Role of Corticotropin-releasing Factor–Toll-like Receptor 4–Proinflammatory Cytokine Signaling

Nozu T, Okumura T

KMID: 2528032
J Neurogastroenterol Motil.
2022 Apr;28(2):173-184.
doi: 10.5056/jnm21002

Irritable bowel syndrome (IBS) displays chronic abdominal pain with altered defecation. Most of the patients develop visceral hypersensitivity possibly resulting from impaired gut barrier and altered gut microbiota. We previously...

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18 Hypnosis to Reduce Distress in Children Undergoing Anorectal Manometry: A Randomized Controlled Pilot Trial

Baaleman DF, Vriesman MH, Koppen IJN, Osborne KM, Benninga MA, Saps M, Yacob D, Lu PL, Woodley FW, Lorenzo CD

KMID: 2528046
J Neurogastroenterol Motil.
2022 Apr;28(2):312-319.
doi: 10.5056/jnm20274

Background/Aims To assess the effectiveness and feasibility of a brief session of hypnosis to reduce distress in children with functional constipation undergoing anorectal manometry (ARM). Methods A partially-blinded randomized controlled pilot trial was conducted...

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19 Functional Neuroimaging in Irritable Bowel Syndrome: A Systematic Review Highlights Common Brain Alterations With Functional Movement Disorders

Nisticò V, Rossi RE, D’Arrigo AM, Priori A, Gambini O, Demartini B

KMID: 2528033
J Neurogastroenterol Motil.
2022 Apr;28(2):185-203.
doi: 10.5056/jnm21079

Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder characterized by recurring abdominal pain and altered bowel habits without detectable organic causes. This study aims to provide a comprehensive...

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20 Development of Dilated Esophagus, Sigmoid Esophagus, and Esophageal Diverticulum in Patients With Achalasia: Japan Achalasia Multicenter Study

Sato H, Fujiyoshi Y, Abe H, Shiwaku H, Shiota J, Sato C, Sakae H, Ominami M, Hata Y, Fukuda H, Ogawa R, Nakamura J, Tatsuta T, Ikebuchi Y, Yokomichi H, Terai S, Inoue H

KMID: 2528036
J Neurogastroenterol Motil.
2022 Apr;28(2):222-230.
doi: 10.5056/jnm21188

Background/Aims Patients with achalasia-related esophageal motility disorders (AEMDs) frequently present with dilated and sigmoid esophagus, and develop esophageal diverticulum (ED), although the prevalence and patients characteristics require further elucidation. Methods We conducted a multicenter...

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