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Measurement of the tear meniscus height using 0.25% fluorescein sodium

Lim KJ, Lee JH

Measuring the tear meniscus height (TMH) is easy after fluorescein installation, but the TMH after fluorescein instillation is higher than the TMH before fluorescein instillation. Therefore, we measured the time...
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Outflow of aqueous humor following cyclodialysis or ciliochoroidal detachment in rabbit

Joo SH, Ko MK, Choe JK

Cyclodialysis and ciliochoroidal detachment were performed in three eyes of three rabbits and in three eyes of another three rabbits, respectively. After aspiration of the aqueous humor, 0.1 ml of...
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Stimulatory Effects of Ginsan on the Proliferation and Viability of Mouse Spleen Cells

Ko EJ, Joo HG

Ginsan is an acidic polysaccharide purified from Panax ginseng, a famous oriental herb. Although a variety of biological activities of ginsan have been studied, the effects of ginsan on spleen...
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Effect of High Glucose on the Production of Reactive Oxygen Species in R28 Cells

Lee JM, Kim JW

  • KMID: 2425092
  • J Korean Ophthalmol Soc.
  • 2010 May;51(5):746-750.
PURPOSE: To investigate the effect of high glucose (HG) on the production of reactive oxygen species (ROS) in retinal precursor R28 cells. METHODS: R28 cells were incubated with low glucose (5...
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Effect of Glucose on the Production of Reactive Oxygen Species in Retinal Pigment Epithelial Cells

Lee JH, Kim JW

PURPOSE: To investigate the effect of high glucose (HG) on the production of reactive oxygen species (ROS) in retinal pigment epithelial (RPE) cells. METHODS: ARPE-19 cells were exposed to low glucose...
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Further Characterization of Activin A-induced IgA Response in Murine B Lymphocytes

Lee HJ, Kim PH

We have recently shown that activin A, a member of TGF-beta superfamily, stimulates mouse B cells to express IgA isotype but other isotypes. In the present study, we further characterized...
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Induction of IL-8 and reactive oxygen species in periodontal ligament cells by Aggregatibacter actinomycetemcomitans

Lee YS, Park HG, Kim SW, Cha JH, Yoo YJ

PURPOSE: Interleukin (IL)-8 is one of pro-inflammatory cytokines. Reactive oxygen species (ROS) are reduced metabolites of O2. Aggregatibacter actinomycetemcomitans is one of representative periodontopathogens. To investigate the role of A....
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Catalase Induced by All-Trans Retinoic Acid Is Involved in Antiproliferation of 36B10 Cells

Park WY, Yu JR

PURPOSE: All-trans retinoic acid (ATRA) has antiproliferative effects against brain tumor cells. Recently, ATRA has been reported to induce catalase. We investigated whether catalase induction by ATRA is associated with...
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Viability of Cells in Aspirated Fat Tissue after 1 Year Cryopreservation

Son D, Oh J, Choi T, Kim J, Han K

  • KMID: 2120359
  • J Korean Soc Plast Reconstr Surg.
  • 2009 Mar;36(2):135-139.
PURPOSE: The use of an autogenous fat graft has become a common procedure in plastic surgery. However, questions remain concerning on the viability of fat cells and preservation method of...
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Fluorescence Quenching to Measure dDAVP-induced Cell Volume Changes in Kidney Collecting Duct Cell

Choi HJ, Kwon TH

  • KMID: 2080003
  • Korean J Nephrol.
  • 2009 Jul;28(4):317-325.
PURPOSE: Cell volume regulation is critical in kidney collecting duct cells which are subjected to large transepithelial osmotic gradients and stimulation of vasopressin. The present study aimed at validating the...
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The effect of dichlorotriazinyl aminofluorescein on human keratocytes in vitro

Wee WR, Rofougaran R, Pakkar A, Hayashi S, McDonnell

Dichlorotriazinyl aminofluorescein (DTAF) has been used to stain corneal stromal collagen as part of in vivo animal experiments for many years. Toxicity of this drug, if present, might alter the...
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Phosphorylation of 14-3-3zeta at serine 58 and neurodegeneration following kainic acid-induced excitotoxicity

Jeong EA, Jeon BT, Kim JB, Kim JS, Cho YW, Lee DH, Kim HJ, Kang SS, Cho GJ, Choi WS, Roh GS

Oxidative stress-induced cell death leads to phosphorylation of 14-3-3zeta at serine 58. 14-3-3zeta is detected at significant levels in cerebrospinal fluid after kainic acid (KA)-induced seizures. Here we examined temporal...
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Immunomodulatory effect of canine periodontal ligament stem cells on allogenic and xenogenic peripheral blood mononuclear cells

Kim HS, Kim KH, Kim SH, Kim YS, Koo KT, Kim TI, Seol YJ, Ku Y, Rhyu IC, Chung CP, Lee YM

PURPOSE: The aim of this study was to investigate the immunomodulatory effects of canine periodontal ligament stem cells on allogenic and xenogenic immune cells in vitro. METHODS: Mixed cell cultures consisting...
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The Effect of Troglitazone on Thermal Sensitivity in Uterine Cervix Cancer Cells

Lee JH, Kim WD, Yu JR, Park WY

PURPOSE: Troglitazone (TRO), a PPAR-gamma agonist, can reduce heat shock protein (HSP) 70 and increase the antioxidant enzymes, such as superoxide dismutase (SOD) and catalase, which might affect thermal sensitivity....
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Effects of NaOCl on Neuronal Excitability and Intracellular Calcium Concentration in Rat Spinal Substantia Gelatinosa Neurons

Lee HI, Park AR, Chun SW

  • KMID: 1431123
  • Int J Oral Biol.
  • 2013 Mar;38(1):5-12.
Recent studies indicate that reactive oxygen species (ROS) can act as modulators of neuronal activity, and are critically involved in persistent pain primarily through spinal mechanisms. In this study, we...
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The Influence of Hypo-Oxygenation or Hyper-Oxygenation on Cell Survival after Paraquat Exposure in A549 Cells

Kim H, Lee SW, Park JS

  • KMID: 1997748
  • J Korean Soc Emerg Med.
  • 2010 Oct;21(5):645-651.
PURPOSE: Paraquat (1,1'-dimethy-4,4'-bipyridinium dichloride, PQ) is a very effective and widely used herbicide that was commercially introduced in 1962. It is reduced by an electron donor such NADPH and then...
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Influence of Aspirin on Pilocarpine-Induced Epilepsy in Mice

Jeong KH, Kim JY, Choi YS, Lee MY, Kim SY

Aspirin (acetylsalicylic acid) is one of the most widely used therapeutic agents based on its pharmacological actions, including anti-inflammatory, analgesic, anti-pyretic, and anti-thrombotic effects. In this study, we investigated the...
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Alterations in the Kinetics of CD4+ T Cell Responses with Aging

Hong MS, Dan JM, Lee WW, Kang I

  • KMID: 2334877
  • J Korean Rheum Assoc.
  • 2009 Dec;16(4):271-280.
OBJECTIVE: Alterations in the immune system occur with aging, and these contribute to an increased risk of infection and malignancy. The age-associated changes in T cell immunity range from single...
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The Protective Effect of Quercetin-3-O-beta-D-Glucuronopyranoside on Ethanol-induced Damage in Cultured Feline Esophageal Epithelial Cells

Cho JH, Park SY, Lee HS, Whang WK, Sohn UD

Quercetin-3-O-beta-D-glucuronopyranoside (QGC) is a flavonoid glucoside extracted from Rumex Aquaticus Herba. We aimed to explore its protective effect against ethanol-induced cell damage and the mechanism involved in the effect in...
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Injury of [correction] Neurons by oxygen-glucose deprivation in organotypic hippocampal slice cultures

Chung DC, Hong KS, Kang J, Chang YP

PURPOSE: We intended to observe cell death and apoptotic changes in neurons in organotypic hippocampal slice cultures following oxygen-glucose deprivation (OGD), using propidium iodide (PI) uptake, Fluoro-Jade (FJ) staining, TUNEL...
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