- Systems Bioinformatics Research Trends
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Lee E, Lee D
- KMID: 2330857
- J Korean Soc Med Inform.
- 2008 Dec;14(4):313-327.
Bioinformatics is the information technology to deal with biological data. Recently emerging systems biology has drawn great interest inspired by world-wide efforts for modeling and analyzing biological processes with a... -
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- Higher Order Knowledge Processing: Pathway Database and Ontologies
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Fukuda KI
- KMID: 1572631
- Genomics Inform.
- 2005 Jun;3(2):47-51.
Molecular mechanisms of biological processes are typically represented as "pathways" that have a graph-analogical network structure. However, due to the diversity of topics that pathways cover, their constituent biological entities... -
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- Writing, erasing and reading histone lysine methylations
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Hyun K, Jeon J, Park K, Kim J
- KMID: 2382715
- Exp Mol Med.
- 2017 Apr;49(4):e324.
- doi: 10.1038/emm.2017.11
Histone modifications are key epigenetic regulatory features that have important roles in many cellular events. Lysine methylations mark various sites on the tail and globular domains of histones and their... -
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- Cardiovascular Molecular Imaging
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Lee KH
- KMID: 2313096
- Nucl Med Mol Imaging.
- 2009 Jun;43(3):229-239.
Molecular imaging strives to visualize processes in living subjects at the molecular level. Monitoring biochemical processes at this level will allow us to directly track biological processes and signaling events... -
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- Recent Progresses in the Linguistic Modeling of Biological Sequences Based on Formal Language Theory
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Park HS, Galbadrakh B, Kim YM
- KMID: 1450880
- Genomics Inform.
- 2011 Mar;9(1):5-11.
Treating genomes just as languages raises the possibility of producing concise generalizations about information in biological sequences. Grammars used in this way would constitute a model of underlying biological processes... -
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- Biological Pathway Extension Using Microarray Gene Expression Data
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Chung TS, Kim J, Kim K, Kim JH
- KMID: 2166420
- Genomics Inform.
- 2008 Dec;6(4):202-209.
Biological pathways are known as collections of knowledge of certain biological processes. Although knowledge about a pathway is quite significant to further analysis, it covers only tiny portion of genes... -
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- Single Molecule Method for Molecular Biology
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Kim JH, Jeong C
- KMID: 2437355
- Int J Oral Biol.
- 2018 Jun;43(2):53-59.
- doi: 10.11620/IJOB.2018.43.2.053
In order to understand biological phenomena accurately, single molecule techniques using a physical research approach to molecular interactions have been developed, and are now widely being used to study complex... -
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- Biology of Aging: Medical Perspective
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Kim KI
- KMID: 2184802
- J Korean Med Assoc.
- 2007 Mar;50(3):216-220.
- doi: 10.5124/jkma.2007.50.3.216
Aging is the most familiar yet least understood aspect of human biology. It is usually defined as the time-dependent progressive loss of function leading to disability, dependence, morbidity, and mortality.... -
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- Analysis of Whole Transcriptome Sequencing Data: Workflow and Software
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Yang IS, Kim S
- KMID: 2166526
- Genomics Inform.
- 2015 Dec;13(4):119-125.
- doi: 10.5808/GI.2015.13.4.119
RNA is a polymeric molecule implicated in various biological processes, such as the coding, decoding, regulation, and expression of genes. Numerous studies have examined RNA features using whole transcriptome sequencing... -
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- Biomarkers of Stroke
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Bang OY
- KMID: 2288729
- Korean J Stroke.
- 2011 Aug;13(2):57-62.
BACKGROUND: Most major clinical trials have failed during the last 2 decades, including large clinical trials of secondary prevention and neuroprotection. These results suggest the presence of heterogeneity among stroke... -
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- Translational Imaging with PET Reporter Gene Approaches
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Min JJ
- KMID: 2139238
- Nucl Med Mol Imaging.
- 2006 Dec;40(6):279-292.
Recent progress in the development of non-invasive imaging technologies continues to strengthen the role of biomedical research. These tools have been validated recently in variety of research models, and have... -
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- Current status and perspectives of researches on programmed cell death in immune system
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Chung YH
- KMID: 2365358
- Allergy.
- 1995 Dec;15(4):569-595.
Programmed cell death(PCD), or apoptosis, is a distinct process of cell death in response to specific physiological or toxic signal. This genetically programmed form of cellular suicide is intimately involved... -
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- Serotonin Outside the Central Nervous System
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Song HR, Woo YS, Bahk WM
- KMID: 2287470
- Korean J Psychopharmacol.
- 2012 Apr;23(2):45-50.
Most serotonin is found outside the central nervous system and functions much more than a neurotransmitter. Peripheral serotonin is produced by enterochromaffin cells in the gastrointestinal tract and secreted into... -
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- Endoscopic Molecular Imaging: Status and Future Perspective
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Muguruma N, Miyamoto H, Okahisa T, Takayama T
- KMID: 2165418
- Clin Endosc.
- 2013 Nov;46(6):603-610.
During the last decade, researchers have made great progress in the development of new image processing technologies for gastrointestinal endoscopy. However, diagnosis using conventional endoscopy with white light optical imaging... -
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- High-concentration Epigallocatechin Gallate Treatment Causes Endoplasmic Reticulum Stress-mediated Cell Death in HepG2 Cells
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Ahn JI, Jeong KJ, Ko MJ, Shin HJ, Chung HJ, Jeong HS
- KMID: 2053228
- Genomics Inform.
- 2009 Jun;7(2):97-106.
Epigallocatechin gallate (EGCG), a well-known antioxidant molecule, has been reported to cause hepatotoxicity when used in excess. However, the mechanism underlying EGCG-induced hepatotoxicity is still unclear. To better understand the... -
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- Roles of Oncogenic Long Non-coding RNAs in Cancer Development
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Do H, Kim W
- KMID: 2439208
- Genomics Inform.
- 2018 Dec;16(4):e18.
- doi: 10.5808/GI.2018.16.4.e18
Long non-coding RNAs (lncRNAs) are classified as RNAs that are longer than 200 nucleotides and cannot be translated into protein. Several studies have demonstrated that lncRNAs are directly or indirectly... -
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- Diagnostic Significance of pH-Responsive Gd³âº-Based Tâ‚ MR Contrast Agents
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Bhuniya S, Hong KS
- KMID: 2442229
- Investig Magn Reson Imaging.
- 2019 Mar;23(1):17-25.
- doi: 10.13104/imri.2019.23.1.17
We discuss recent advances in Gd-based Tâ‚-weighted MR contrast agents for the mapping of cellular pH. The pH plays a critical role in various biological processes. During the past two... -
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- In Vivo Cell Tracking with Bioluminescence Imaging
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Kim JE, Kalimuthu , Ahn BC
- KMID: 2313239
- Nucl Med Mol Imaging.
- 2015 Mar;49(1):3-10.
- doi: 10.1007/s13139-014-0309-x
Molecular imaging is a fast growing biomedical research that allows the visual representation, characterization and quantification of biological processes at the cellular and subcellular levels within intact living organisms. In... -
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- Will Molecular Optical Imaging Have Clinically Important Roles in Stroke Management, and How?
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Lee DK, Nahrendorf M, Schellingerhout D, Kim DE
- KMID: 2135476
- J Clin Neurol.
- 2010 Mar;6(1):10-18.
- doi: 10.3988/jcn.2010.6.1.10
Molecular imaging is a novel technology to visualize biological processes at the cellular and molecular levels, which is reshaping both biomedical research and clinical practice. By providing molecular information to... -
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- Biological Meaning of the Histo-Blood Group Antigens Composed of Sugar Chains
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Kwon SW, Ahn A, Chung Y
- KMID: 2255807
- Korean J Blood Transfus.
- 2015 Aug;26(2):103-122.
- doi: 10.17945/kjbt.2015.26.2.103
All living creatures on this planet, from bacteria to human, produce sugar chains (glycans). This means that sugar chains are essential for living a life. Abundant, diverse, and highly regulated... -
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