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Association of HLA-A, B antigens with Susceptibility to Advanced Endometriosis in Koreans

Whang DH, Kim SH, Park MH, Choi YM

BACKGROUND: Endometriosis is defined as the presence of endometrial tissue outside the uterus, causing diverse diseases, including infertility, pelvic pain, dysmenorrhea, and constipation. While there is a growing body...
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Absence of HLA-B*1502 and HLA-A*3101 Alleles in 9 Korean Patients With Antiepileptic Drug-Induced Skin Rash: A Preliminary Study

Song JS, Kang ES, Joo EY, Hong SB, Seo DW, Lee SY

There have been a number of studies about correlations between HLA genotypes in various ethnic groups and occurrence of various cutaneous adverse drug reactions, ranging in intensity from mild to...
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Occult hepatitis B virus infection: clearance or disguise?

Kim JW

No abstract available.
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Emergence of vaccine-induced escape mutant of hepatitis b virus with multiple surface gene mutations in a korean child

Lee KM, Kim YS, Ko YY, Yoo BM, Lee KJ, Kim JH, Hahm KB, Cho SW

The S protein of hepatitis B virus is the principal component of virus envelope and the primary target of anti-HBs response. Mutants or variants that escape neutralization by anti-HBs have...
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The First Known Case of Blood Group Chimerism in Monochorionic Dizygotic Twins in Korea

Lee OJ, Cho D, Shin MG, Kim SO, Park JT, Kim HK, Ryang DW

No abstract available.
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Allelic and Haplotypic Diversity of HLA-A, -B, -C, and -DRB1 Genes in Koreans Defined by High-resolution DNA Typing

Chung HY, Yoon JA, Han BY, Song EY, Park MH

BACKGROUND: In this study, we used high-resolution DNA typing to investigate the distribution of HLA alleles and haplotypes in Koreans. METHODS: HLA-A, -B, -C, and -DRB1 alleles were genotyped at...
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Behcet's Disease: The First Mongolian Case in Literature Showing HLA B51, MICA Gene Type *5/*6

Chung YL, Bang DS, Lee ES, Lee SN, Mok JW, Park KS

  • KMID: 2428367
  • Yonsei Med J.
  • 2003 Oct;44(5):935-938.
Behcet's disease is a chronic multi-systemic disease of unknown origin that includes mucocutaneous, ocular, cardiac, vascular, renal, gastrointestinal, neurologic and cutaneous involvement. The disease is spread throughout the world, but...
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Immunohistochemical study on antigenic phenotype of Langerhans cell histiocytosis

Yang WI

Immunohistochemical study on 26 cases of Langerhans cell histiocytosis (LCH) using several leukocyte antibodies in addition to traditionally used markers (S-100 protein and peanut agglutinin) revealed that the proliferating cells...
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The tumor necrosis factor beta * 1 allele is linked significantly to HLA-DR8 in Koreans with atrophic autoimmune thyroiditis who are positive for thyrotropin receptor blocking antibody

Chung JH, Cho BY, Lee HK, Kim TG, Han H, Koh CS

The localization and functional characteristics of tumor necrosis factor(TNF) beta gene raise the possibility that it may be involved in the susceptibility to autoimmune thyroid diseases. To investigate whether a...
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Evaluation of BioSewoom(TM) HLA-A, -B, -C PCR/SSP Kit

Cha CH, Kim MH, Chung HJ, Choi SE, Oh HB

BACKGROUND: Human leukocyte antigen (HLA) typing based on polymerase chain reaction (PCR) is rapidly replacing the conventional serological method. This study was intended to evaluate Bio- SewoomTM HLA-A, -B,...
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Hepatitis B Viral Surface Mutations in Patients with Adefovir Resistant Chronic Hepatitis B with A181T/V Polymerase Mutations

Kim JH, Jung YK, Joo MK, Kim JH, Yim HJ, Park JJ, Kim JS, Bak YT, Yeon JE, Byun KS

The hepatitis B virus (HBV) polymerase gene has overlapping reading frames with surface genes, which allows to alter the amino acid codon of the surface genes. In adefovir (ADV) treated...
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Human Leukocyte Antigen Class II Association with Spontaneous Recovery from Hepatitis B Virus Infection in Koreans: Analysis at the Haplotype Level

Cho SW, Cheong JY, Ju YS, Oh DH, Suh YJ, Lee KW

It has been speculated that human leukocyte antigen (HLA) alleles are associated with the outcome of hepatitis B virus (HBV) infection although the data obtained from various populations have shown...
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Recent Trends of Antigenic Variation in Bordetella pertussis Isolates in Korea

Kim SH, Lee J, Sung HY, Yu JY, Kim SH, Park MS, Jung SO

Pertussis is a representative vaccine-preventable disease. However, there have been recent outbreaks in countries where even higher vaccination against the disease. One reason is the emergence of antigenic variants, which...
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Resolution of Ambiguous HLA Genotyping in Korean by Multi-Group-Specific Sequence-Based Typing

Park Y, Yoon CE, Kwon OJ, Kim YS, Kim HS

PURPOSE: To evaluate a multi-group-specific sequence-based typing (SBT) method for resolving ambiguous results from human leukocyte antigen (HLA) genotyping. MATERIALS AND METHODS: A total of 50 samples that showed ambiguous genotypes...
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Certain Polymorphisms in SP110 Gene Confer Susceptibility to Tuberculosis: A Comprehensive Review and Updated Meta-Analysis

Zhang S, Wang XB, Han YD, Wang C, Zhou Y, Zheng F

PURPOSE: Numerous studies have assessed the association of SP110 gene variants with tuberculosis (TB), but the results were inconsistent. Through a comprehensive review and meta-analysis, our study aimed to clarify...
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Association of MICA Polymorphism with HLA-B51 and Disease Severity in Korean Patients with Behcet's Disease

Park SH, Park KS, Seo YI, Min DJ, Kim WU, Kim TG, Cho CS, Mok JW, Park KS, Kim HY

The HLA-B51 allele is known to be associated with Behcet's disease (BD) in many ethnic group. However, it has not yet been clarified whether the HLA-B51 gene itself is the...
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Associations of Moyamoya Patients with HLA Class I and Class II Alleles in the Korean Population

Han H, Pyo CW, Yoo DS, Huh PW, Cho KS, Kim DS

Moyamoya disease is characterized by progressive cerebrovascular occlusion at the peripheral internal carotid artery and development of abnormal collateral circulation at the cerebral basal region. Although abnormal thrombogenesis, inflammation and...
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HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs

Park HJ, Kim YJ, Kim DH, Kim J, Park KH, Park JW, Lee JH

PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction. SJS/TEN induced by certain drug is well known to be associated with...
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HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy

Jeong JH, Hong SC, Shin YK, Han JH, Lee SP

Cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the frequency of the HLA-DQB1 allele and cerebrospinal fluid (CSF) hypocretin levels in Korean...
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Human Leukocyte Antigen-C Genotype and Killer Immunoglobulin-like Receptor-Ligand Matching in Korean Living Donor Liver Transplantation

Lee H, Park KH, Park HS, Ryu JH, Lim J, Kim Y, Na GH, Kim DG, Oh EJ

BACKGROUND: The interaction between killer immunoglobulin-like receptors (KIRs) and HLA class I regulates natural killer (NK) cell cytotoxicity and function. The impact of NK cell alloreactivity through KIR in liver...
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