J Prev Med Public Health.  2008 May;41(3):153-158. 10.3961/jpmph.2008.41.3.153.

Epidemiological Investigation of a Measles Outbreak in a Preschool in Incheon, Korea, 2006

Affiliations
  • 1Division of Vaccine Preventable Disease Control & National Immunization Program, Centers for Disease Control & Prevention, Seoul, Korea. kayser-so@hanmail.net
  • 2Division of Infectious Disease Surveillance, Centers for Disease Control & Prevention, Seoul, Korea.
  • 3Centers for Disease Control & Prevention, Seoul, Korea.

Abstract


OBJECTIVES
This study describes a plan that was designed to prevent a measles outbreak that showed a changed outbreak pattern. This study is based on the epidemiological investigation of a measles outbreak in a preschool in Incheon, Korea, 2006.
METHODS
The subjects were 152 students at a preschool where a measles outbreak occurred. A questionnaire survey was conducted and serological testing for measlesspecific IgM was preformed.
RESULTS
Of the fifteen confirmed, identified cases, eleven patients had been vaccinated with one dose, one patient had received two doses and three patients were unvaccinated. The three unvaccinated cases consisted of one 5-year-old child, one 3-year-old child and one 16-month-old infant. For the cases with one dose of the vaccination, there were 11 cases, which consisted of six 5-year-old children, two 4-year-old children, two 3-year-old children and one 2-year-old child. The case with two doses of the vaccination was one 4-year-old child. The attack rate of measles was 100% in the 0-dose group, 11.2% in the 1-dose group and 2.0% in the 2-dose group. The vaccine's efficacy was 88.8% in the 1-dose group and 98.0% in the 2-dose group. The vaccine effectiveness for the 2-dose group was higher than that of the 1-dose group.
CONCLUSIONS
High coverage with a 2-dose vaccination should be maintained, and the vaccination should be given at the suitable time to prevent a measles outbreak with a changed outbreak pattern.

Keyword

Measles; Outbreak; Vaccination

MeSH Terms

Child, Preschool
*Disease Outbreaks/prevention & control
Humans
Immunization Programs
Korea
Measles/*epidemiology/immunology/*prevention & control/virology
Measles Vaccine/*administration & dosage
Preventive Medicine
Questionnaires
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