Korean J Gastroenterol.  2007 May;49(5):331-335.

A Case of Photodynamic Therapy for Early Esophageal Cancer Recurred after Esophagectomy

  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. jikim@catholic.ac.kr


Photodynamic therapy is a promising modality for the palliation of advanced upper gastrointestinal cancer and for the eradication of early neoplastic and pre-neoplastic lesions. It is based on the combination of a photosensitizer that is selectively localized in the target tissue and illumination of the lesion with visible light, resulting in photodamage and subsequent cell death. For early esophageal cancer, esophagectomy has been a standard modality of curative intent. However, accumulated data supports the possibility of PDT replacing surgery as a curative modality. We experienced a case of early esophageal cancer that recurred after esophagectomy. The patient was successfully treated with photodynamic therapy using porfimer sodium as a photosensitizer.


Photodynamic therpy; Early esophageal cancer; Second primary malignancy
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