Korean J Hepatol.  2004 Sep;10(3):228-232.

Extrahepatic Metastasis of Hepatocellular Carcinoma to the Nasal Cavity Manifested as Massive Epistaxis: A Case Report

Affiliations
  • 1Center for Liver Cancer, National Cancer Center, Goyang, Korea. 1000jay@hanmail.net
  • 2Hepatobilliary-pancreatic Cancer Branch, National Cancer Center, Goyang, Korea.
  • 3Center for Specific Organs Cancer, National Cancer Center, Goyang, Korea.

Abstract

Extrahepatic metastasis of hepatocellular carcinoma (HCC) is not infrequently found during the later stage, regarding that the autopsy report described its prevalence to be up to 50%. The most frequent sites are known to be the abdominal lymph nodes, lung and bone. However, metastasis to the nasal cavity and paranasal sinuses has been seldom reported, and to out knowledge, there is no Korean report describing extrahepatic metastasis of HCC to these sites. Recently we experienced a case of extrahepatic metastasis of HCC to the nasal cavity in a 50 year-old man with massive epistaxis refractory to conservative treatment. He was found to have a mass of soft tissue attenuation occupying the right nasal cavity at CT, which was biopsy-proven as metastatic HCC. Epistaxis was successfully treated by transcatheter arterial embolization.

Keyword

Hepatocellular carcinoma; Metastasis; Nasal cavity; Epistaxis

MeSH Terms

Carcinoma, Hepatocellular/*secondary
English Abstract
Epistaxis/*etiology
Humans
Liver Neoplasms/*pathology
Male
Middle Aged
*Nasal Cavity
Nose Neoplasms/complications/diagnosis/*secondary
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