Korean J Intern Med.  2006 Dec;21(4):262-265. 10.3904/kjim.2006.21.4.262.

Anorectal and gastric peripheral T-cell lymphoma, unspecified in a non-AIDS patient

Affiliations
  • 1Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea. kimhawk@uuh.ulsan.kr
  • 2Department of Pathology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea.

Abstract

Anorectum is a rare location for malignant lymphoma. Involvement of is rare even for the lymphoma associated with acquired immune deficiency syndrome (AIDS), and AIDS has a relatively increased frequency of anorectal lymphoma. Most lymphomas in AIDS patients are of a B-cell origin, and T-cell lymphoma of the gastrointestinal tract is extremely rare. We report here on a case of anorectal and gastric peripheral T-cell lymphoma, unspecified (PTCLu) in a non-AIDS patient. A previously healthy 29-year-old man presented with hematochezia and tenesmus that he had suffered with for the previous 2 months. Sigmoidoscopy showed anal and rectal submucosal tumor. Multiple round-shaped, flat and elevated lesions were noted on the gastric antrum and body as well. He underwent excisional biopsy for the anal mass and the diagnosis was PTCLu. Biopsies of the gastric lesions gave the same diagnosis. There was no lymphoma involved in the bone marrow. At admission, no antibodies against human immunodeficiency virus were detected. He underwent systemic chemotherapy and upfront autologous stem cell transplantation.

Keyword

Rectum; Peripheral T-cell lymphoma unspecified; Non-AIDS

MeSH Terms

Tomography, X-Ray Computed
Stomach Neoplasms/*pathology/radiography
Sigmoidoscopy
Rectal Neoplasms/*pathology/radiography
Male
Lymphoma, T-Cell, Peripheral/*pathology/radiography
Humans
Gastroscopy
Follow-Up Studies
Diagnosis, Differential
Biopsy
Adult
Acquired Immunodeficiency Syndrome/*diagnosis
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