Korean J Intern Med.  2003 Mar;18(1):50-52.

Hypersensitivity to Mosquito Bites Associated with Natural Killer Cell-derived Large Granular Lymphocyte Lymphocytosis: A Case Report in Korea

Affiliations
  • 1Department of Internal Medicine, Pusan National University College of Medicine, Busan, Korea.
  • 2Department of Clinical Pathology, Pusan National University College of Medicine, Busan, Korea.

Abstract

Hypersensitivity to mosquito bites (HMB) is characterized by intense skin reactions at bite sites. The pathogenesis of HMB might be related to clonal lymphoproliferation of Epstein-Barr virus DNA-positive natural killer (NK) cells. We report the first case of HMB possibly associated with NK cell-derived large granular lymphocyte (NK-LGL) lymphocytosis in Korea.

Keyword

Hypersensitivity; Mosquito bites; Natural killer cell; Large granular lymphocyte lymphocytosis

MeSH Terms

Adult
Animals
Base Sequence
*Culicidae
Epstein-Barr Virus Infections/*complications/diagnosis
Humans
Hypersensitivity/*etiology/virology
Insect Bites and Stings/*complications/immunology
Killer Cells, Natural/*immunology/pathology
Korea
Lymphocytosis/*complications/pathology
Male
Molecular Sequence Data
Polymerase Chain Reaction
Prognosis
Risk Assessment
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