Korean J Ophthalmol.  2006 Dec;20(4):238-240. 10.3341/kjo.2006.20.4.238.

A Case of Scar Sarcoidosis of The Eyelid

Affiliations
  • 1Department of Ophthalmology, Seoul Veterans Hospital, Seoul, Korea.
  • 2Department of Ophthalmology, Saumsung Medical Center, School of Medicine Sungkyunkwan University, Seoul, Korea. ydkim@ smc.samsung.co.kr

Abstract

PURPOSE: We report the case of a patient with scar sarcoidosis that developed along a previous eyelid scar. There was no evidence of ocular or systemic sarcoidosis. METHODS: A 29-year-old man presented with a mass on his right eyelid that had been present for two month. On ocular examination an erythematous, firm, and non-tender mass was diffusely palpable along the upper and lower eyelid scar. We performed an incisional biopsy of the lower lid mass. RESULTS: Histopathologic examination of the mass revealed numerous, noncaseating granulomas with multi-nucleated giant cells. The giant cells contained asteroid bodies and calcium oxalate crystals characteristic of sarcoidosis, although the patient had no other evidence of systemic sarcoidosis. The mass in the upper lid disappeared after intralesional triamcinolone injections. CONCLUSIONS: This case represents a rare occurrence of sarcoidosis that arose in an old eyelid scar. Scar sarcoidosis should be considered in the differential diagnosis of an unusual mass in a scar.

Keyword

Non-caseating granuloma; Scar sarcoidosis; Triamcinolone injection

MeSH Terms

Triamcinolone/administration & dosage
Sarcoidosis/drug therapy/etiology/*pathology
Male
Injections, Intralesional
Humans
Glucocorticoids/administration & dosage
Follow-Up Studies
Eyelids/injuries
Eyelid Diseases/drug therapy/etiology/*pathology
Eye Injuries/complications
Diagnosis, Differential
Cicatrix/complications/*pathology
Biopsy
Adult

Figure

  • Fig. 1 An erythematous firm mass is visible along the upper and lower eyelid scar.

  • Fig. 2 A photomicrograph of the biopsy showing the numerous, noncaseating granulomas with multi-nucleated giant cells, surrounded by lymphocytes. (hematoxylin and eosin stain, ×200)

  • Fig. 3 A photomicrograph of the biopsy showing the giant cells containing asteroid bodies (arrow). (hematoxylin and eosin stain, ×400)

  • Fig. 4 A photomicrograph of the biopsy showing the calcium oxalate crystals (arrow). (hematoxylin and eosin stain, ×200)

  • Fig. 5 One month after triamcinolone injection, there was a dramatic resolution of the lesions of the upper lid mass.


Cited by  1 articles

A Case of Sarcoidosis Presented as Multiple Conjunctival and Nasal Mucosal Nodule
In-Cheon You, Hyung-Jin Moon, Gwi-Hyeong Mun, Sang-Chul Im, Kyung-Chul Yoon
J Korean Ophthalmol Soc. 2008;49(6):1000-1006.    doi: 10.3341/jkos.2008.49.6.1000.


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