Korean J Ophthalmol.  2001 Dec;15(2):81-86. 10.3341/kjo.2001.15.2.81.

Serum factors associated with neovascular glaucoma following vitrectomy for proliferative diabetic retinopathy

• Kim YH
• Suh Y
• Yoo JS

• KMID: 754301
• DOI: http://doi.org/10.3341/kjo.2001.15.2.81

Abstract

We performed a retrospective study of serum factors associated with neovascular glaucoma that can occur following vitrectomy for proliferative diabetic retinopathy. The medical records of 183 patients (241 eyes) who received vitrectomy between August 1996 and August 2000 were studied retrospectively and subsequently analyzed by linear logistic regression analysis and multiple logistic regression tests. Neovascular glaucoma developed at an average of 2.7 months in 31 of 241 eyes (14.1%). The overall anatomical success rate of retinal attachment was 82.5% (199 eyes in 241 eyes), although it decreased to 45.1% (14 eyes in 31 eyes) in eyes with neovascular glaucoma. Serum cholesterol (P = 0.041) and fibrinogen levels (P = 0.020) were significantly associated with the development of neovascular glaucoma. However, no significant association could be found concerning hypertension, diabetic retinopathy or hypercholesterolemia (P > 0.05). We suggest that serum creatinine, cholesterol and fibrinogen levels can be used to predict the development of neovascular glaucoma in vitrectomized eyes with diabetic retinopathy and can further provide a more active approach to preventing the development of this condition.

Keyword

Diabetic Retinopathy; Neovascular glaucoma; serum factors; Vitrectomy

MeSH Terms

Adult
Aged
Aged, 80 and over
Blood/metabolism
Cell Division
Diabetic Retinopathy/*pathology/*surgery
Glaucoma, Neovascular/*blood/*complications
Human
Middle Age
Postoperative Period
Retrospective Studies
*Vitrectomy