Yonsei Med J.
1998 Dec;39(6):578-586. 10.3349/ymj.1998.39.6.578.
Antimicrobial resistance patterns of Bacteroides fragilis group organisms in Korea
- Affiliations
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- 1Department of Clinical Pathology, Yonsei University College of Medicine, Seoul, Korea. leekcp@yumc.yonsei.ac.kr
- 2Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.
- KMID: 711601
- DOI: http://doi.org/10.3349/ymj.1998.39.6.578
Abstract
- Antimicrobial resistance patterns of 913 clinical isolates of Bacteroides fragilis group organisms were monitored during an 8-year period in Korea. In general the resistance rates of the non-fragilis B. fragilis group species were higher than those of B. fragilis for all the drugs tested. The rate of resistance to clindamycin remarkably increased and those to some beta-lactam drugs such as piperacillin and cefotaxime also increased. No isolates were found to be resistant to imipenem, metronidazole, or chloramphenicol. beta-lactam and beta-lactamase inhibitor combinations and cefoxitin were more active than the other beta-lactams. Therefore, these agents may be considered when empirical selection of antimicrobial agents is required to treat severe anaerobic infections.
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