J Korean Med Sci.
1994 Aug;9(4):347-350. 10.3346/jkms.1994.9.4.347.
A case of nephrotic syndrome associated with protein S deficiency and cerebral thrombosis
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- 1Department of Clinical Pathology, College of Medicine, Yonsei University, Seoul, Korea.
- KMID: 644819
- DOI: http://doi.org/10.3346/jkms.1994.9.4.347
Abstract
- Protein S is found in two forms in plasma; as free and functionally active protein S, and complexed to C4b-binding protein. Patients with nephrotic syndrome are at risk for arterial and venous thrombosis at various localizations, and acquired protein S deficiency due to the selective urinary loss of the free form may be a risk factor for the development of thromboembolic complications. We report a case of cerebral arterial thrombosis associated with decreased level of free protein S antigen (44%) in a 39-year-old female patient with nephrotic syndrome.
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Cited by 2 articles
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Cerebral Infarction as a Complication of Nephrotic Syndrome: A Case Report with a Review of the Literature
Yeo Wook Yun, Sungjin Chung, Sun-Jin You, Dong Kyu Lee, Kyu-Yong Lee, Sang-Woong Han, Heng Ok Jee, Ho-Jung Kim
J Korean Med Sci. 2004;19(2):315-319. doi: 10.3346/jkms.2004.19.2.315.Central Retinal Artery Obstruction in Protein S Deficiency
Sung Bok Lee, Yong Jun Yun, Jung Yeul Kim
J Korean Ophthalmol Soc. 2008;49(12):2017-2020. doi: 10.3341/jkos.2008.49.12.2017.
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