J Korean Orthop Assoc.  2025 Dec;60(4):321-325. 10.4055/jkoa.2025.60.4.321.

Recurrent Fungal Infection of the Elbow Joint Due to CARD9 Deficiency: A Rare Genetic Cause of Fungal Infection

• Chang AS
• Yoo HS
• Moon JG

• KMID: 2574921
• DOI: http://doi.org/10.4055/jkoa.2025.60.4.321

Abstract

Recurrent fungal infections of the elbow joint are extremely rare. This paper reports a case of a caspase recruitment domain family member 9 (CARD9) deficiency, a genetic disorder characterized by impaired antifungal immunity, which is diagnosed in a young and relatively healthy male patient who presented with persistent fungal infection. In recurrent fungal infections without identifiable risk factors, clinicians should consider the possibility of an underlying genetic immunodeficiency and perform genetic testing when appropriate.

Keyword

elbow; mycoses; CARD9 deficiency