J Neurogastroenterol Motil.  2025 Oct;31(4):407-421. 10.5056/jnm24181.

Insights Into Functional Dyspepsia and Gastroparesis – Western Versus Asian Perspectives

• Ziyang JK
• Kuo B

• KMID: 2573087
• DOI: http://doi.org/10.5056/jnm24181

Abstract

Functional dyspepsia and gastroparesis are common gastrointestinal conditions that can significantly impact a patient’s quality of life. Management of these conditions can be challenging for the treating physician due to overlap in symptomatology and incomplete response to conventional medications such as proton pump inhibitors and prokinetics. There is a growing trend in the use of management strategies such as neuromodulators, psycho-behavioral therapy, and other alternative treatments including acupuncture. Notably, differences exist in the epidemiology, symptom expression, and disease management in Western versus Asian patients. These differences stem from varying accessibility to investigation tests and medications, dietary habits and cultural beliefs. This review article comprehensively summarizes the latest knowledge on the approach to the evaluation and management of functional dyspepsia and gastroparesis, and explores the different factors influencing management practices in the West as compared to in Asia.

Keyword

Asia; Functional dyspepsia; Gastroparesis; West