J Korean Med Sci.  2025 Aug;40(32):e196. 10.3346/jkms.2025.40.e196.

Impact of Qualified Trauma Center Implementation on Mortality From Severe Trauma in Korea: A Retrospective Cohort Study

Affiliations
  • 1Division of Trauma Surgery, Department of Surgery, Ajou University School of Medicine, Suwon, Korea
  • 2Ajou University Hospital Gyeonggi South Regional Trauma Center, Suwon, Korea
  • 3Division of Biostatistics, Department of Population Health, New York University Grossman School of Medicine, New York, NY, USA

Abstract

Background
The Korean government and experts initiated a national trauma system development project in 2012. Its first major initiative was establishing and operating regional trauma centers across the country. We assessed whether the severity-adjusted mortality rates were lower in trauma centers compared with non-trauma centers and the specific benefits of trauma centers for patients with trauma.
Methods
This retrospective cohort study analyzed the data of patients with trauma registered in the National Emergency Department Information System from 2015 to 2019. Additionally, we used the Korean Trauma Data Bank and trauma center status data provided by the Ministry of Health and Welfare. We focused on patients with survival probabilities of < 0.5 according to the International Classification of Diseases Injury Severity Score, 9th Edition. The severity-adjusted mortality rates between the trauma centers and non-trauma centers were compared.
Results
The 7 qualified trauma centers had notably more younger patients with penetrating injuries than the non-trauma centers. Patients admitted to the trauma centers had more critical vital signs and a higher incidence of reduced consciousness than those admitted to the non-trauma centers. After adjusting for severity, the in-hospital mortality rates were significantly lower in the trauma centers than in the non-trauma centers (16.9% vs. 18.2%; relative risk, 0.933; 95% confidence interval, 0.874–0.997). Patients in shock conditions had significantly lower mortality rates when treated in trauma centers. The disparity in cumulative mortality rates between the trauma centers and non-trauma centers was most pronounced 2 days post-admission.
Conclusion
This study confirmed that the national project for establishing regional trauma centers effectively reduced mortality rates among severely injured patients.

Keyword

Wounds and Injuries; Mortality; Korea; Trauma Centers

Reference

1. Centers for Disease Control and Prevention. Leading causes of death reports, 1981–2020. Updated 2021. Accessed December 1, 2024. https://wisqars.cdc.gov/animated-leading-causes/ .
3. World Health Organization. Injuries and violence: the facts 2014. Updated 2015. Accessed December 1, 2024. https://www.who.int/publications/i/item/9789241508018 .
4. GBD 2019 Diseases and Injuries Collaborators. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet. 2020; 396(10258):1204–1222. PMID: 33069326.
5. Drake SA, Holcomb JB, Yang Y, Thetford C, Myers L, Brock M, et al. Establishing a regional trauma preventable/potentially preventable death rate. Ann Surg. 2020; 271(2):375–382. PMID: 30067544.
6. Haas B, Gomez D, Zagorski B, Stukel TA, Rubenfeld GD, Nathens AB. Survival of the fittest: the hidden cost of undertriage of major trauma. J Am Coll Surg. 2010; 211(6):804–811. PMID: 21036070.
7. Haas B, Stukel TA, Gomez D, Zagorski B, De Mestral C, Sharma SV, et al. The mortality benefit of direct trauma center transport in a regional trauma system: a population-based analysis. J Trauma Acute Care Surg. 2012; 72(6):1510–1515. PMID: 22695414.
8. Ray JJ, Meizoso JP, Satahoo SS, Davis JS, Van Haren RM, Dermer H, et al. Potentially preventable prehospital deaths from motor vehicle collisions. Traffic Inj Prev. 2016; 17(7):676–680. PMID: 26890273.
9. MacKenzie EJ, Rivara FP, Jurkovich GJ, Nathens AB, Frey KP, Egleston BL, et al. A national evaluation of the effect of trauma-center care on mortality. N Engl J Med. 2006; 354(4):366–378. PMID: 16436768.
10. Jung KY, Kim JS, Kim Y. Problems in trauma care and preventable deaths. J Korean Soc Emerg Med. 2001; 12(1):45–56.
11. Kim Y, Jung KY, Cho KH, Kim H, Ahn HC, Oh SH, et al. Preventable trauma deaths rates and management errors in emergency medical system in Korea. J Korean Soc Emerg Med. 2006; 17(5):385–394.
12. Kim H, Jung KY, Kim SP, Kim SH, Noh H, Jang HY, et al. Changes in preventable death rates and traumatic care systems in Korea. J Korean Soc Emerg Med. 2012; 23(2):189–197.
13. Im J, Seo EW, Jung K, Kwon J. Understanding regional trauma centers and managing a trauma care system in South Korea: a systematic review. Ann Surg Treat Res. 2023; 104(2):61–70. PMID: 36816735.
14. Korea Ministry of Government Legislation. National law information system emergency medical service act. Updated 2013. Accessed December 1, 2024. https://www.law.go.kr/LSW//lsInfoP.do?lsiSeq=140932&chrClsCd=010203&urlMode=engLsInfoR&viewCls=engLsInfoR#0000 .
15. National Emergency Medical Center. History of EMS in Korea. Updated 2023. Accessed December 1, 2024. https://www.e-gen.or.kr/nemc/business_preventable_trauma.do .
16. Korean National Emergency Medical Center. Emergency medical statistics annual report 2019. Updated 2019. Accessed December 1, 2024. https://www.e-gen.or.kr/nemc/statistics_annual_report.do?brdclscd=02 .
17. Korean National Emergency Medical Center. National emergency department information system in Korea 2022. Updated 2023. Accessed December 1, 2024. https://www.e-gen.or.kr/nemc/statistics_annual_report.do?brdclscd=04 .
18. World Health Organization. Chapter XIX: injury, poisoning and certain other consequences of external causes. International Statistical Classification of Diseases and Related Health Problems. 10th Revision. Geneva, Switzerland: World Health Organization;2016. p. 791–892.
19. Moore L, Champion HR. Injury severity scoring, modeling, and outcomes research. Feliciano DV, Mattox KL, Moore EE, editors. Trauma. 9th ed. New York, NY, USA: McGraw Hill;2021. p. 71–94.
20. Osler T, Rutledge R, Deis J, Bedrick E. ICISS: an International Classification of Disease-9 based injury severity score. J Trauma. 1996; 41(3):380–386. PMID: 8810953.
21. Little RJA, Rubin DB. Statistical Analysis with Missing Data. Vol. 793. Hoboken, NJ, USA: John Wiley & Sons;2019.
22. Rubin D. Multiple Imputation for Nonresponse in Surveys. Hoboken, NJ, USA: John Wiley & Sons, Inc.;1987.
23. Robins JM, Hernán MA, Brumback B. Marginal structural models and causal inference in epidemiology. Epidemiology. 2000; 11(5):550–560. PMID: 10955408.
24. Nathens AB, Jurkovich GJ, Rivara FP, Maier RV. Effectiveness of state trauma systems in reducing injury-related mortality: a national evaluation. J Trauma. 2000; 48(1):25–30. PMID: 10647561.
25. Celso B, Tepas J, Langland-Orban B, Pracht E, Papa L, Lottenberg L, et al. A systematic review and meta-analysis comparing outcome of severely injured patients treated in trauma centers following the establishment of trauma systems. J Trauma. 2006; 60(2):371–378. PMID: 16508498.
26. Cameron PA, Gabbe BJ, Cooper DJ, Walker T, Judson R, McNeil J. A statewide system of trauma care in Victoria: effect on patient survival. Med J Aust. 2008; 189(10):546–550. PMID: 19012550.
27. Moran CG, Lecky F, Bouamra O, Lawrence T, Edwards A, Woodford M, et al. Changing the system – major trauma patients and their outcomes in the NHS (England) 2008–17. EClinicalMedicine. 2018; 2-3:13–21.
28. Candefjord S, Asker L, Caragounis EC. Mortality of trauma patients treated at trauma centers compared to non-trauma centers in Sweden: a retrospective study. Eur J Trauma Emerg Surg. 2022; 48(1):525–536. PMID: 32719897.
29. Hsia RY, Wang E, Saynina O, Wise P, Pérez-Stable EJ, Auerbach A. Factors associated with trauma center use for elderly patients with trauma: a statewide analysis, 1999-2008. Arch Surg. 2011; 146(5):585–592. PMID: 21242421.
30. Chang DC, Bass RR, Cornwell EE, Mackenzie EJ. Undertriage of elderly trauma patients to state-designated trauma centers. Arch Surg. 2008; 143(8):776–781. PMID: 18711038.
31. Hoyle AC, Biant LC, Young M. Undertriage of the elderly major trauma patient continues in major trauma centre care: a retrospective cohort review. Emerg Med J. 2020; 37(8):508–514. PMID: 32546474.
32. Biffl WL, Harrington DT, Majercik SD, Starring J, Cioffi WG. The evolution of trauma care at a level I trauma center. J Am Coll Surg. 2005; 200(6):922–929. PMID: 15922206.
33. Härtl R, Gerber LM, Iacono L, Ni Q, Lyons K, Ghajar J. Direct transport within an organized state trauma system reduces mortality in patients with severe traumatic brain injury. J Trauma. 2006; 60(6):1250–1256. PMID: 16766968.
34. Ehrlich PF, Rockwell S, Kincaid S, Mucha P Jr. American College of Surgeons, Committee on Trauma verification review: does it really make a difference? J Trauma. 2002; 53(5):811–816. PMID: 12435927.
35. Janagama SR, Newberry JA, Kohn MA, Rao GVR, Strehlow MC, Mahadevan SV. Is AVPU comparable to GCS in critical prehospital decisions? - a cross-sectional study. Am J Emerg Med. 2022; 59:106–110. PMID: 35820277.
36. Trunkey DD, Lim RC. Analysis of 425 consecutive trauma fatalities: an autopsy study. JACEP. 1974; 3(6):368–371.
37. Jencks SF, Williams MV, Coleman EA. Rehospitalizations among patients in the Medicare fee-for-service program. N Engl J Med. 2009; 360(14):1418–1428. PMID: 19339721.
38. Meislin H, Criss EA, Judkins D, Berger R, Conroy C, Parks B, et al. Fatal trauma: the modal distribution of time to death is a function of patient demographics and regional resources. J Trauma. 1997; 43(3):433–440. PMID: 9314304.
39. Nathens AB, Cryer HG, Fildes J. The American College of Surgeons trauma quality improvement program. Surg Clin North Am. 2012; 92(2):441–454. x–xi. PMID: 22414421.
40. Nathens AB, Jurkovich GJ, Cummings P, Rivara FP, Maier RV. The effect of organized systems of trauma care on motor vehicle crash mortality. JAMA. 2000; 283(15):1990–1994. PMID: 10789667.
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