Acute Crit Care.  2025 Feb;40(1):1-9. 10.4266/acc.004896.

Dialysis decision in critically ill patients in intensive care unit

Affiliations
  • 1Department of Nephrology, Pusan National University School of Medicine, Yangsan, Korea
  • 2Biomedical Research Institute, Pusan National University Hospital, Busan, Korea

Abstract

The 2012 Kidney Disease Improving Global Outcomes guidelines clearly define emergent indications for kidney replacement therapy; however, whether dialysis should be initiated in critically ill patients without these indications remains unclear. This review briefly summarizes the results of recent landmark trials and discusses their limitations originating from a criteria-based approach at a single time point. Moreover, a personalized approach based on each patient’s demand-capacity balance and its future benefits as a platform for kidney support therapy in critically ill patients are discussed.

Keyword

acute kidney injury; critical illness; kidney replacement therapy; kidney support therapy; time-to-treatment
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