Exp Neurobiol.
2025 Apr;34(2):49-52. 10.5607/en25006.
Astrocytic Ornithine Decarboxylase 1 in Alzheimer’s Disease
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- 1Center for Cognition and Sociality, Institute for Basic Science, Daejeon 34126, Korea
- KMID: 2569190
- DOI: http://doi.org/10.5607/en25006
Abstract
- Recent research has shed light on the metabolic changes in reactive astrocytes associated with Alzheimer’s disease, contributing to disease pathology. In this article, we summarize key findings related to reactive astrogliosis and how the discovery of the role of the enzyme ornithine decarboxylase 1 can set us on the path to finding more effective therapeutic strategies against neurodegenerative diseases.
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