J Adv Prosthodont.  2023 Apr;15(2):80-92. 10.4047/jap.2023.15.2.80.

Adhesion of biofilm, surface characteristics, and mechanical properties of antimicrobial denture base resin

• Teixeira ABV
• Valente MLdC
• Sessa JPN
• Gubitoso B
• Schiavon MA
• dos Reis AC

• KMID: 2541805
• DOI: http://doi.org/10.4047/jap.2023.15.2.80

Abstract

PURPOSE
This study incorporated the nanomaterial, nanostructured silver vanadate decorated with silver nanoparticles (AgVO₃), into heat-cured resin (HT) at concentrations of 2.5%, 5%, and 10% and compared the adhesion of multispecies biofilms, surface characteristics, and mechanical properties with conventional heat-cured (HT 0%) and printed resins.
MATERIALS AND METHODS
AgVO₃ was incorporated in mass into HT powder. A denture base resin was used to obtain printed samples. Adhesion of a multispecies biofilm of Candida albicans, Candida glabrata, and Streptococcus mutans was evaluated by colony-forming units per milliliter (CFU/mL) and metabolic activity. Wettability, roughness, and scanning electron microscopy (SEM) were used to assess the physical characteristics of the surface. The mechanical properties of flexural strength and elastic modulus were tested.
RESULTS
HT 10%-AgVO₃ showed efficacy against S. mutans; however, it favored C. albicans CFU/mL (P < .05). The printed resin showed a higher metabolically active biofilm than HT 0% (P < .05). There was no difference in wettability or roughness between groups (P > .05). Irregularities on the printed resin surface and pores in HT 5%-AgVO₃ were observed by SEM. HT 0% showed the highest flexural strength, and the resins incorporated with AgVO₃ had the highest elastic modulus (P < .05).
CONCLUSION
The incorporation of 10% AgVO₃ into heat-cured resin provided antimicrobial activity against S. mutans in a multispecies biofilm did not affect the roughness or wettability but reduced flexural strength and increased elastic modulus. Printed resin showed higher irregularity, an active biofilm, and lower flexural strength and elastic modulus than heat-cured resin.

Keyword

Antimicrobial; Heat-cured resin; 3D print resin; Silver nanoparticles