Osong Public Health Res Perspect.  2022 Dec;13(6):448-452. 10.24171/j.phrp.2022.0235.

A low risk of nosocomial transmission of subclinical tuberculosis to neonates in a postpartum care center under COVID-19 control measures

Affiliations
  • 1Division of Infectious Disease Response, Capital Regional Center for Disease Control and Prevention, Seoul, Korea
  • 2Gimhae Airport National Quarantine Station, Busan, Korea
  • 3Division of Public Health Administration, Suji-gu Public Health Center, Yongin, Korea
  • 4Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 5Graduate School of Global Development and Entrepreneurship, Handong Global University, Pohang, Korea

Abstract

We report the results of investigating and managing a tuberculosis (TB) exposure in a postpartum care center. Among the contacts exposed to a nursing assistant with subclinical TB, 5 of 44 neonates (11.4%) had positive tuberculin skin tests (TSTs) at 3 months of age, and all the TST-positive neonates received the Bacille Calmette-Guérin vaccination. Seven of 28 healthcare workers (25.0%) and 1 of 3 household contacts (33.3%) were positive in the initial or repeated interferon-gamma release assay. None of the contacts developed TB disease during the study period. Annual TB examinations of healthcare personnel at a postpartum care center under the Tuberculosis Prevention Act in South Korea enabled the early detection of subclinical TB, which reduced the risk of transmission to neonates under strict coronavirus disease 2019 prevention measures.

Keyword

Latent tuberculosis; Neonates; Postpartum period; Pulmonary tuberculosis
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