J Korean Soc Radiol.  2022 Nov;83(6):1385-1393. 10.3348/jksr.2022.0019.

Imaging Findings of Metaplastic Breast Carcinoma with Chondroid Differentiation: A Case Reports

Affiliations
  • 1Department of Radiology, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Korea
  • 2Department of Surgery, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Korea
  • 3Department of Pathology, Inje University College of Medicine, Sanggye Paik Hospital, Seoul, Korea

Abstract

Metaplastic carcinoma of the breast is a heterogeneous group of neoplasms with mixed epithelial and mesenchymal differentiation. Metaplastic carcinoma of the breast is a rare and aggressive malignancy, with high recurrence and metastasis. Metaplastic carcinoma with chondroid differentiation is an uncommon subtype that tends to have a relatively good prognosis than that of other subtypes. We report the imaging features of three cases of pathologically proven metaplastic carcinoma with chondroid differentiation as follows: a high-density mass with amorphous or coarse heterogeneous calcifications on mammography; a microlobulated or partially indistinct, complex cystic, and solid mass on sonography; and a relatively circumscribed or partially indistinct, irregular mass with heterogeneous T2 high-signal intensity and heterogeneous or rim enhancement with initial fast enhance ment and delayed washout on MRI.

Keyword

Breast Cancer; Metaplasia; Mammography; Ultrasound; Magnetic Resonance Imaging
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