Infect Chemother.  2022 Sep;54(3):534-541. 10.3947/ic.2022.0101.

The Incidence and Risk Factors of Renal Insufficiency among Korean HIV infected Patients: The Korea HIV/AIDS Cohort Study

Affiliations
  • 1Division of Infectious Diseases, Department of Internal Medicine, Chungbuk National University Hospital, Cheongju, Korea
  • 2Department of Preventive Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 3Division of Infectious Diseases, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea
  • 4AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea
  • 5Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea
  • 6Division of Infectious Diseases, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea
  • 7Division of Infectious Diseases, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
  • 8Department of Preventive Medicine, Hanyang University College of Medicine, Seoul, Korea

Abstract

Renal insufficiency is one of the common issues in people living with human immunodeficiency virus (PLHIV). We studied the incidence and risk factors for renal insufficiency in male PLHIV using the Korea HIV/acquired immunodeficiency syndrome (AIDS) Cohort Study. Among the 830 enrolled patients, 32 (3.9%) cases of renal insufficiency occurred over 9576 patient-years of follow-up. The incidence of renal insufficiency in HIVinfected men in this study was 3.3 per 1000 patient-years. Diabetes mellitus, dyslipidemia, tenofovir or non-nucleoside reverse transcriptase inhibitor exposure for >1 year, and AIDSdefining illness were risk factors for renal insufficiency.

Keyword

HIV/AIDS; Renal insufficiency; Cohort study
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