Infect Chemother.  2022 Sep;54(3):393-408. 10.3947/ic.2022.0060.

Myths and Misconceptions around Antibiotic Resistance: Time to Get Rid of Them

• Amábile-Cuevas CF

• KMID: 2534153
• DOI: http://doi.org/10.3947/ic.2022.0060

Abstract

The antibiotic resistance arena is fraught with myths and misconceptions, leading to wrong strategies to combat it. It is crucial to identify them, discuss them in light of current evidence, and dispel those that are unequivocally wrong. This article proposes some concepts that may qualify as misconceptions around antibiotic resistance: the susceptible–resistant dichotomy; that incomplete antibiotic courses cause resistance; that resistance “emerges” in patients and hospitals; that antibiotics are mostly abused clinically; that resistance is higher in countries that use more antibiotics; that reducing antibiotic usage would reduce resistance; that financial incentives would “jumpstart” research and development of antibiotics; that generic and “original” antibiotics are the same; and that new anti-infective therapies are just around the corner. While some of these issues are still controversial, it is important to recognize their controversial status, instead of repeating them in specialized literature and lectures and, especially, in the planning of strategies to cope with resistance.

Keyword

Antibiotic resistance; Antibiotic usage; Treatment adherence; Generic antibiotics; Antibiotic R&D