Korean J Dermatol.  2022 Sep;60(8):522-526.

Adult-Onset Atypical Spitz Nevus on the Abdomen: A Case Report

  • 1Department of Dermatology, School of Medicine, Kyung Hee University, Seoul, Korea


Atypical Spitz nevi are defined as melanocytic proliferations with intermediate histopathologic features between those of Spitz nevi and Spitzoid melanoma. Diagnosis of atypical Spitz nevi can be challenging, and there remains a lack of consensus among dermatopathologists regarding an exact definition. A 59-year-old female presented with an asymptomatic, 1.2-×0.8-cm-sized erythematous nodule on the abdomen. Histopathological findings demonstrated spindle and epithelioid cells with prominent nucleoli in nests from the dermo-epidermal junction to the reticular dermis with a few epidermal pagetoids spread. Immunohistochemical analysis revealed positive S-100, negative HMB-45, and a Ki-67 index of 10%. A final diagnosis of atypical Spitz nevus was made, and the tumor was resected via total surgical excision. Herein, we report a rare case of adult-onset atypical Spitz nevus on the abdomen.


Atypical spitz nevus; Spitz tumor
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