J Obes Metab Syndr.  2022 Sep;31(3):277-281. 10.7570/jomes22042.

Association between Obesity and Length of COVID-19 Hospitalization: Unexpected Insights from the American Heart Association National COVID-19 Registry

Affiliations
  • 1Division of Hospital Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
  • 2Department of Epidemiology and Population Health, Stanford University School of Medicine, Stanford, CA, USA
  • 3Stanford Cardiovascular Institute, Stanford University, Stanford, CA, USA
  • 4Quantitative Sciences Unit, Center for Biomedical Informatics Research, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
  • 5Division of Cardiovascular Medicine, Department of Medicine, University of California San Francisco School of Medicine, San Francisco, CA, USA
  • 6Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA

Abstract

Background
The mechanism for possible association between obesity and poor clinical outcomes from Coronavirus Disease 2019 (COVID-19) remains unclear.
Methods
We analyzed 22,915 adult COVID-19 patients hospitalized from March 2020 to April 2021 to non-intensive care using the American Heart Association National COVID Registry. A multivariable Poisson model adjusted for age, sex, medical history, admission respiratory status, hospitalization characteristics, and laboratory findings was used to calculate length of stay (LOS) as a function of body mass index (BMI). We similarly analyzed 5,327 patients admitted to intensive care for comparison.
Results
Relative to normal BMI subjects, overweight, class I obese, and class II obese patients had approximately half-day reductions in LOS (–0.469 days, P<0.01; –0.480 days, P<0.01; –0.578 days, P<0.01, respectively).
Conclusion
The model identified a dose-dependent, inverse relationship between BMI category and LOS for COVID-19, which was not seen when the model was applied to critically ill patients.

Keyword

Obesity; Hospitalization; Length of stay; COVID-19
Full Text Links
  • JOMES
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2023 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr