Int J Heart Fail.  2022 Jul;4(3):145-153. 10.36628/ijhf.2022.0002.

In-Hospital Mortality Rate and Predictors of 30-Day Readmission in Patients With Heart Failure Exacerbation and Atrial Fibrillation: A Cross-Sectional Study

Affiliations
  • 1Division of Hospital Medicine, Department of Medicine, University of Missouri, Columbia, MO, USA
  • 2Division of Hospital Medicine, Department of Medicine, John H. Stroger Hospital of Cook County, Chicago, IL, USA
  • 3Division of Interventional Cardiology, Department of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA
  • 4Department of Medicine, Pandit Deendayal Upadhyay Medical College, Rajkot, India
  • 5Division of Heart and Vascular, Department of Cardiology, John H. Stroger Hospital of Cook County, Chicago, IL, USA

Abstract

Background and Objectives
Heart failure (HF) and atrial fibrillation (AF) are considered new cardiovascular epidemics of the last decade. Recent national trends show an uptrend in HF hospitalizations. We aimed to identify the 30-day readmission rate, causes, and impact on healthcare utilization in HF exacerbation with a history of AF.
Methods
We utilized 2018 Nationwide readmission data and included patients aged ≥18 years with International Classification of Diseases, Tenth Revision, Clinical Modification code indicating HF exacerbation and AF were included in the study. Primary outcome is 30-day readmission rates. Secondary outcomes were mortality rates, common causes of readmission, and healthcare utilization. Independent predictors for readmission were identified using cox regression analysis.
Results
The total number of admissions in our study was 48,250. The mean age was 77.8 years (standard deviation, 12.1), and 47.74% were females. The 30-day readmission rate was 16.72%. The mortality rate at index admission and readmission was 7.28% and 8.12%, respectively. The most common cause of readmission was the hypertensive heart and kidney disease with HF. The independent predictors of readmission were low socio-economic class, Medicaid, Charlson comorbidities score. The financial burden on healthcare for all the readmission was $461 million for the year 2018.
Conclusions
The 30-day readmission rate was 16.72%. The mortality rate increased from 7.28% to 8.12% with readmission. The financial burden for readmission during that year was $461 million. Future studies directed with interventions to prevents readmissions are warranted.

Keyword

Thirty-day readmission; Diastolic heart failure; Systolic heart failure; Atrial fibrillation
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