J Chest Surg.  2022 Aug;55(4):288-292. 10.5090/jcs.22.056.

Ex Vivo Lung Perfusion in Lung Transplantation

Affiliations
  • 1Department of Thoracic and Cardiovascular Surgery, Ajou University School of Medicine, Suwon, Korea

Abstract

Ex vivo lung perfusion (EVLP) is a technique that enables active metabolism of the lung by creating an environment similar to that inside the body, even though the explanted lungs are outside the body. The EVLP system enables the use of lung grafts that do not satisfy the acceptance criteria for lung transplantation (LTx) by making it possible to evaluate the function of the lung grafts and repair lungs in poor condition, thereby reducing the waiting time of patients requiring LTx and consequently mortality.

Keyword

Lung transplantation; Donor pool; Ex vivo lung perfusion
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