J Korean Neuropsychiatr Assoc.  2022 May;61(2):74-79. 10.4306/jknpa.2022.61.2.74.

The Willingness of Enduring Drug Side Effects in the Patients of Depressive Disorders: From the Results of Korean Nationwide Patients’ Perspectives Survey Study

• Ko M
• Song HR
• Kim SY
• Jung YE
• Kim W
• Seo JS
• Sohn I
• Lee K
• Lee JH
• Chung SK
• Lee SY
• Hong JW
• Yoon BH
• Woo YS
• Bahk WM

• KMID: 2529979
• DOI: http://doi.org/10.4306/jknpa.2022.61.2.74

Abstract

Objectives
There has been increased use of medications in treating depressive disorders. Nowadays, patient value is an important part of prescribing medications. This study examines depressive patients’ perspectives on the side effects of medications.
Methods
We administered questionnaires nationwide to 364 patients with depressive disorders. Intent or willingness to endure 21 side effects from the Antidepressant Side-Effect Checklist (ASEC) were examined and compared in patients who are less than mildly ill and who are more than moderately ill.
Results
In the population, decreased appetite, yawning, increased body temperature, dry mouth, sweating, and constipation are regarded as generally endurable side effects. In contrast, dizziness, light-headedness, nausea or vomiting, headaches, disorientation, problems with urination, and difficulty sleeping are hard to endure. There were differences between patients who are less than mildly ill and those who are more than moderately ill regarding the willingness to endure drowsiness, decreased appetite, sexual dysfunction, palpitations, and weight gain.
Conclusion
This nationwide study revealed a general willingness in depressed patients to endure side effects. Sensitive and premeditative discussions of patient value with regard to medications might contribute to finding successful treatments.

Keyword

Depressive patients; Perspectives; Side effects