Clin Pediatr Hematol Oncol.  2022 Apr;29(1):17-20. 10.15264/cpho.2022.29.1.17.

Colo-Colic Intussusception as the Presenting Feature of Neutropenic Typhlitis during Induction Phase of Acute Lymphoblastic Leukemia in an 8-Year-Old Child

• Pal S
• Krishnan Y
• Sainulabdin G
• Parameswaran KV

• KMID: 2529686
• DOI: http://doi.org/10.15264/cpho.2022.29.1.17

Abstract

Acute lymphoblastic leukemia (ALL) is the most common malignancy of children. Gastrointestinal complications can occur during treatment of these children due to disease infiltration in gut or treatment-related toxicity. Intestinal obstruction is one of these complications and this occurs mostly due to constipation and impacted stool. Intussusception is a very rare entity in children with ALL. Left sided colo-colic intussusception is even rarer. Most of the intussusceptions are ileo-colic and are associated with a lead point. We present a case of left sided colo-colic intussusception in an 8-year-old child with ALL. There was no lead point or leukemic infiltrate in the resected part of the intussusception. Our child had typhlitis leading to intussusception which is a very rare occurrence. Awareness regarding this complication with ALL is important for prompt diagnosis and treatment.

Keyword

Acute lymphoblastic leukemia; Colo-colic; Intussusception