Diabetes Metab J.  2022 Mar;46(2):297-306. 10.4093/dmj.2021.0038.

Prevalence of Type 2 Diabetes Mellitus among Korean Children, Adolescents, and Adults Younger than 30 Years: Changes from 2002 to 2016

Affiliations
  • 1Department of Pediatrics, Soonchunhyang University Bucheon Hospital, Soonchunhyang University College of Medicine, Bucheon, Korea
  • 2Department of Pediatrics, National Health Insurance Service Ilsan Hospital, Goyang, Korea
  • 3Department of Statistics and Actuarial Science, Soongsil University, Seoul, Korea
  • 4Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
  • 5Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Korea

Abstract

Background
Despite the importance of and social concern regarding prevention of diabetes at younger ages, limited data are available. This study sought to analyze changes in the prevalence of type 2 diabetes mellitus (T2DM) in Koreans younger than 30 years according to sex, age, and level of income.
Methods
The dataset analyzed in this study was derived from health insurance claims recorded in the National Health Insurance Service (NHIS) database. Participants’ level of income was categorized as low (quintile 1, <20% of insurance premium) or others (quintile 2–5).
Results
In males and females, the prevalence of T2DM per 10,000 people steadily increased from 2.57 in 2002 to 11.41 in 2016, and from 1.96 in 2002 to 8.63 in 2016. The prevalence of T2DM in girls was higher in the age group of 5 to 14 years. Even though the prevalence was higher among those older than 20 years, the increase had started earlier, in the early 2000s, in younger age group. Adolescents aged 10 to 19 years in low-income families showed a remarkable increase in prevalence of T2DM, especially in boys.
Conclusion
The prevalence of T2DM in young Koreans increased more than 4.4-fold from 2002 to 2016, and the increase started in the early 2000s in younger age groups and in low-income families. This is the first study to examine the trend in prevalence of T2DM in children, adolescents, and young adults in Korea. Future studies and collaborations with social support systems to prevent T2DM at an early age group should be performed.

Keyword

Adolescent; Child; Diabetes mellitus, type 2; Prevalence; Young adult

Figure

  • Fig. 1. The prevalence of type 2 diabetes mellitus per 10,000 people among Korean children, adolescents, and young adults younger than 30 years of age from 2002 to 2016. A difference in the slope between male and female is confirmed with the test for trend, P (P=0.015).

  • Fig. 2. The prevalence of type 2 diabetes mellitus per 10,000 people stratified by sex and age among Korean children, adolescents, and young adults younger than 30 years of age from 2002 to 2016. Differences in the slope between groups are confirmed with the test for trend, P. aP for trend <0.05.

  • Fig. 3. The prevalence of type 2 diabetes mellitus per 10,000 people stratified by sex, age, and level of income among Korean children, adolescents, and young adults younger than 30 years of age from 2002 to 2016. Differences in the slope between groups are confirmed with the test for trend, P. Mo, male other (quintile 2–5); ML, male low income (quintile 1); Fo, female other (quintile 2–5); FL, female low income (quintile 1). aP for trend <0.05.


Cited by  3 articles

Trends and Risk Factors of Metabolic Syndrome among Korean Adolescents, 2007 to 2018 (Diabetes Metab J 2021;45:880-9)
Dae Jung Kim
Diabetes Metab J. 2022;46(2):349-350.    doi: 10.4093/dmj.2021.0353.

Diagnostic and Therapeutic Strategies of Type 2 Diabetes Mellitus in Youth
Hwa Young Kim, Jae Hyun Kim
Ewha Med J. 2022;45(3):e3.    doi: 10.12771/emj.2022.e3.

Characteristics of Glycemic Control and Long-Term Complications in Patients with Young-Onset Type 2 Diabetes
Han-sang Baek, Ji-Yeon Park, Jin Yu, Joonyub Lee, Yeoree Yang, Jeonghoon Ha, Seung Hwan Lee, Jae Hyoung Cho, Dong-Jun Lim, Hun-Sung Kim
Endocrinol Metab. 2022;37(4):641-651.    doi: 10.3803/EnM.2022.1501.


Reference

1. Kaufman FR. Type 2 diabetes mellitus in children and youth: a new epidemic. J Pediatr Endocrinol Metab. 2002; 15 Suppl 2:737–44.
Article
2. Jung CH, Son JW, Kang S, Kim WJ, Kim HS, Kim HS, et al. Diabetes fact sheets in Korea, 2020: an appraisal of current status. Diabetes Metab J. 2021; 45:1–10.
Article
3. Lascar N, Brown J, Pattison H, Barnett AH, Bailey CJ, Bellary S. Type 2 diabetes in adolescents and young adults. Lancet Diabetes Endocrinol. 2018; 6:69–80.
Article
4. Gungor N, Arslanian S. Progressive beta cell failure in type 2 diabetes mellitus of youth. J Pediatr. 2004; 144:656–9.
Article
5. Nadeau KJ, Anderson BJ, Berg EG, Chiang JL, Chou H, Copeland KC, et al. Youth-onset type 2 diabetes consensus report: current status, challenges, and priorities. Diabetes Care. 2016; 39:1635–42.
Article
6. Magliano DJ, Sacre JW, Harding JL, Gregg EW, Zimmet PZ, Shaw JE. Young-onset type 2 diabetes mellitus: implications for morbidity and mortality. Nat Rev Endocrinol. 2020; 16:321–31.
Article
7. Sattar N, Rawshani A, Franzen S, Rawshani A, Svensson AM, Rosengren A, et al. Age at diagnosis of type 2 diabetes mellitus and associations with cardiovascular and mortality risks. Circulation. 2019; 139:2228–37.
Article
8. Rhodes ET, Prosser LA, Hoerger TJ, Lieu T, Ludwig DS, Laffel LM. Estimated morbidity and mortality in adolescents and young adults diagnosed with type 2 diabetes mellitus. Diabet Med. 2012; 29:453–63.
Article
9. Fazeli Farsani S, van der Aa MP, van der Vorst MM, Knibbe CA, de Boer A. Global trends in the incidence and prevalence of type 2 diabetes in children and adolescents: a systematic review and evaluation of methodological approaches. Diabetologia. 2013; 56:1471–88.
Article
10. Alberti G, Zimmet P, Shaw J, Bloomgarden Z, Kaufman F, Silink M, et al. Type 2 diabetes in the young: the evolving epidemic: the international diabetes federation consensus workshop. Diabetes Care. 2004; 27:1798–811.
11. Dabelea D, Mayer-Davis EJ, Saydah S, Imperatore G, Linder B, Divers J, et al. Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009. JAMA. 2014; 311:1778–86.
Article
12. Cockram CS. The epidemiology of diabetes mellitus in the Asia-Pacific region. Hong Kong Med J. 2000; 6:43–52.
13. Chi X, Yu D, Ju L, Zhang J, Zhao L. Prevalence of diabetes and change among 7 to 17 years old children and adolescents in China in 2002-2012. Wei Sheng Yan Jiu. 2018; 47:705–15.
14. Fu JF, Liang L, Gong CX, Xiong F, Luo FH, Liu GL, et al. Status and trends of diabetes in Chinese children: analysis of data from 14 medical centers. World J Pediatr. 2013; 9:127–34.
Article
15. Hannon TS, Janosky J, Arslanian SA. Longitudinal study of physiologic insulin resistance and metabolic changes of puberty. Pediatr Res. 2006; 60:759–63.
Article
16. Zeitler P, Arslanian S, Fu J, Pinhas-Hamiel O, Reinehr T, Tandon N, et al. ISPAD clinical practice consensus guidelines 2018: type 2 diabetes mellitus in youth. Pediatr Diabetes. 2018; 19 Suppl 27:28–46.
Article
17. Mayer-Davis EJ, Lawrence JM, Dabelea D, Divers J, Isom S, Dolan L, et al. Incidence trends of type 1 and type 2 diabetes among youths, 2002-2012. N Engl J Med. 2017; 376:1419–29.
Article
18. Nam HK, Kim HR, Rhie YJ, Lee KH. Trends in the prevalence of extreme obesity among Korean children and adolescents from 2001 to 2014. J Pediatr Endocrinol Metab. 2017; 30:517–23.
Article
19. McGavock J, Wicklow B, Dart AB. Type 2 diabetes in youth is a disease of poverty. Lancet. 2017; 390:1829.
Article
20. Dabelea D, Stafford JM, Mayer-Davis EJ, D’Agostino R Jr, Dolan L, Imperatore G, et al. Association of type 1 diabetes vs type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood. JAMA. 2017; 317:825–35.
Article
21. Copeland KC, Zeitler P, Geffner M, Guandalini C, Higgins J, Hirst K, et al. Characteristics of adolescents and youth with recent-onset type 2 diabetes: the TODAY cohort at baseline. J Clin Endocrinol Metab. 2011; 96:159–67.
Article
22. Klingensmith GJ, Tamborlane WV, Wood J, Haller MJ, Silverstein J, Cengiz E, et al. Diabetic ketoacidosis at diabetes onset: still an all too common threat in youth. J Pediatr. 2013; 162:330–4.
23. Klingensmith GJ, Connor CG, Ruedy KJ, Beck RW, Kollman C, Haro H, et al. Presentation of youth with type 2 diabetes in the Pediatric Diabetes Consortium. Pediatr Diabetes. 2016; 17:266–73.
Article
24. Kim NH, Kim TJ, Kim NH, Choi KM, Baik SH, Choi DS, et al. Relative and combined effects of socioeconomic status and diabetes on mortality: a nationwide cohort study. Medicine (Baltimore). 2016; 95:e4403.
25. Noh J, Han KD, Ko SH, Ko KS, Park CY. Trends in the pervasiveness of type 2 diabetes, impaired fasting glucose and comorbidities during an 8-year-follow-up of nationwide Korean population. Sci Rep. 2017; 7:46656.
Article
26. Park YS, Lee DH, Choi JM, Kang YJ, Kim CH. Trend of obesity in school age children in Seoul over the past 23 years. Korean J Pediatr. 2004; 47:247–57.
27. Pediatric Obesity Committee of Korean Society for the Study of Obesity. Obesity in children and adolescents. 3rd ed. Seoul: Chung Woon;2019. p. 2.
28. Kim JH, Moon JS. Secular trends in pediatric overweight and obesity in Korea. J Obes Metab Syndr. 2020; 29:12–7.
Article
29. Nam GE, Kim YH, Han K, Jung JH, Rhee EJ, Lee SS, et al. Obesity fact sheet in Korea, 2019: prevalence of obesity and abdominal obesity from 2009 to 2018 and social factors. J Obes Metab Syndr. 2020; 29:124–32.
Article
30. Arslanian S, Bacha F, Grey M, Marcus MD, White NH, Zeitler P. Evaluation and management of youth-onset type 2 diabetes: a position statement by the American Diabetes Association. Diabetes Care. 2018; 41:2648–68.
Article
31. Brar PC. Update on the current modalities used to screen high risk youth for prediabetes and/or type 2 diabetes mellitus. Ann Pediatr Endocrinol Metab. 2019; 24:71–7.
Article
Full Text Links
  • DMJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr