Korean J Health Promot.  2022 Mar;22(1):26-39. 10.15384/kjhp.2022.22.1.26.

Development of a Questionnaire for the Personalized Health Functional Food

Affiliations
  • 1Department of Applied Biomedical Engineering, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea
  • 2Center for Convergence Approaches in Drug Development (CCADD), Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea
  • 3Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul, Korea
  • 4Department of Family Medicine, Hallym University College of Medicine, Chuncheon, Korea
  • 5Institute on Aging, Seoul National University College of Medicine, Seoul, Korea
  • 6Department of Clinical Pharmacology and Therapeutics, Seoul National University Hospital, Seoul, Korea
  • 7Advanced Institute of Convergence Technology, Suwon, Korea

Abstract

Background
This study describes the development of a multi-dimensional questionnaire for the personalized recommendation of health functional foods.
Methods
The questionnaire was designed to include two parts: common and detailed. Each question was formulated based on clinical evidence and physician-administered diagnostic tools provided by reputable sources such as government agencies and medical institutions. The common questions were intended to assess overall health status. The detailed questions were organized into 28 categories based on the classification of health functional foods’ health claims by the Ministry of Food and Drug Safety. Each question’s response was evaluated on a scale from 0 to 1. The final score of each category was calculated as the sum of the scores normalized by the number of questions in each category. Two expert physicians in health functional food assessed the content validity of the questionnaire, and the questionnaire was revised accordingly.
Results
A total of 31 common questions evaluated overall health conditions based on demographic information, medical history, allergies, prescription medicines, dietary habits, and lifestyle. A question that surveys interest areas was also included to let the responders choose up to three categories for the detailed question part. A total of 173 detailed questions assessed risk factors and symptoms relevant to each health claim.
Conclusions
This questionnaire recommends health functional foods by measuring health risks and symptoms, following the classification of health functional foods by the Ministry of Food and Drug Safety. This questionnaire may serve as an evidence-based information collecting tool for a personalized health functional foods recommendation system.

Keyword

Dietary supplements; Health surveys; Diagnostic self evaluation; Health promotion; Delivery of health care

Figure

  • Figure 1. Scheme for developing a questionnaire for recommending personalized health functional foods and ingredients.


Reference

1. Kim KJ, Kim EJ, Song YR, Kim YJ, Jeon SH, Kim JY. Current status of personalized dietary supplement. J Korean Soc Food Sci Nutr. 2020; 25(2):20–37.
2. Jeon YM, Won JH, Lee DSU, Hong S, Lee Y, Choi S, et al. Development of a questionnaire for personalized health functional food [Internet]. Figshare; 2021 [cited Jan 15, 2022]. Available from: https://figshare.com/projects/Development_of_a_questionnaire_for_personalized_health_functional_food/128324.
3. Kaplan GA, Camacho T. Perceived health and mortality: a nine-year follow-up of the human population laboratory cohort. Am J Epidemiol. 1983; 117(3):292–304.
Article
4. Ministry of Food and Drug Safety. Health functional food information by function [Internet]. Cheongju: Ministry of Food and Drug Safety [cited Apr 1, 2021]. Available from: https://www.foodsafetykorea.go.kr/portal/healthyfoodlife/functionality.do?menu_grp=MENU_NEW01&menu_no=2657.
5. Caselli RJ, Dueck AC, Osborne D, Sabbagh MN, Connor DJ, Ahern GL, et al. Longitudinal modeling of age-related memory decline and the APOE ε4 effect. N Engl J Med. 2009; 361(3):255–63.
Article
6. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve cognition and memory [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 5, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14373&srchFr=&srchTo=&srchWord=%EC%9D%B8%EC%A7%80%EA%B8%B0%EB%8A%A5&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
7. Seoul National University Hospital. Medical Encyclopedia [Internet]. Seoul: Seoul National University Hospital [cited May 1, 2021]. Available from: http://www.snuh.org/health/encyclo/search.do.
8. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve sleep quality [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 25, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13687&srchFr=&srchTo=&srchWord=%ED%99%94%EC%9E%A5%ED%92%88&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=3.
9. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to relaxation of tension by stress [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 5, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14655&srchFr=&srchTo=&srchWord=%EA%B8%B4%EC%9E%A5&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
10. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to relieve fatigue [Internet]. Cheongju: Ministry of Food and Drug Safety; 2014 [cited Apr 7, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13235&srchFr=&srchTo=&srchWord=%ED%94%BC%EB%A1%9C%EA%B0%9C%EC%84%A0&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
11. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help with oral health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13685&srchFr=&srchTo=&srchWord=%EC%B9%98%EC%95%84&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
12. Korean Academy of Periodontology. PQ(Perio-Quotient) Test [Internet]. Seoul: Korean Academy of Periodontology; 2013 [cited Apr 20, 2021]. Available from: https://www.kperio.org/bbs/board.php?tbl=news&mode=VIEW&num=33&chr=&category=&findType=&findWord=pq&sort1=&sort2=&bMode=&nPub=&nYear=&sNumber=&sKeyword=&page=1.
13. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Eye health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 7, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14656&srchFr=&srchTo=&srchWord=%EB%88%88+%EA%B1%B4%EA%B0%95&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
14. Ames SL, Wolffsohn JS, Mcbrien NA. The development of a symptom questionnaire for assessing virtual reality viewing using a head-mounted display. Optom Vis Sci. 2005; 82(3):168–76.
Article
15. Guinot C, Malvy DJ, Ambroisine L, Latreille J, Mauger E, Tenenhaus M, et al. Relative contribution of intrinsic vs extrinsic factors to skin aging as determined by a validated skin age score. Arch Dermatol. 2002; 138(11):1454–60.
Article
16. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to maintain healthy skin [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 15, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14376&srchFr=&srchTo=&srchWord=%ED%94%BC%EB%B6%80%EA%B1%B4%EA%B0%95&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
17. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Immune hypersensitivity reaction [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14657&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=110.
18. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Liver health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 5, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14653&srchFr=&srchTo=&srchWord=%EA%B0%84+%EA%B1%B4%EA%B0%95&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
19. Korea Pharmaceutical Information Center. Idiosyncratic drug induced liver injury [Internet]. Seoul: Korea Pharmaceutical Information Center [cited May 10, 2021]. Available from: http://www.health.kr/Menu.PharmReview/_uploadfiles/%ED%8A%B9%EC%9D%B4%EC%A0%81%EC%95%BD%EC%9D%B8%EC%84%B1%EA%B0%84%EC%86%90%EC%83%81_%EC%A0%80%EC%9E%902%EC%B0%A8%EA%B2%80%ED%86%A0%EC%99%84%EB%A3%8C_%EC%B5%9C%EC%A2%85.pdf.
20. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Stomach health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 5, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14659&srchFr=&srchTo=&srchWord=%EC%9C%84+%EA%B1%B4%EA%B0%95&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
21. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Intestine health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14660&srchFr=&srchTo=&srchWord=%EC%9E%A5+%EA%B1%B4%EA%B0%95&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
22. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to reduce body fat [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14369&srchFr=&srchTo=&srchWord=%EC%B2%B4%EC%A7%80%EB%B0%A9&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
23. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to support the absorption of calcium [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13686&srchFr=&srchTo=&srchWord=%EC%B9%BC%EC%8A%98%ED%9D%A1%EC%88%98&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
24. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to modulate blood glucose [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 15, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14371&srchFr=&srchTo=&srchWord=%ED%98%88%EB%8B%B9&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
25. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help improve menopausal women’s health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14374&srchFr=&srchTo=&srchWord=%EA%B8%B0%EB%8A%A5&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=3.
26. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve andropausal men’s health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14375&srchFr=&srchTo=&srchWord=%EA%B8%B0%EB%8A%A5&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=3.
27. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve premenstrual syndrome condition [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13243&srchFr=&srchTo=&srchWord=%EC%9B%94%EA%B2%BD&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
28. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help maintain healthy blood cholesterol level [Internet]. Cheongju: Ministry of Food and Drug Safety; 2019 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14372&srchFr=&srchTo=&srchWord=%EC%BD%9C%EB%A0%88%EC%8A%A4%ED%85%8C%EB%A1%A4&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
29. The Korean Society of Hypertension. Hypertension treatment guidelines [Internet]. Seoul: The Korean Society of Hypertension; 2018 [cited Apr 25, 2021]. Available from: http://www.koreanhypertension.org/reference/guide?mode=read&idno=4246.
30. SAMSUNG Medical Center. Vascular age self-testing [Internet]. SAMSUNG Medical Center [cited Apr 15, 2021]. Available from: http://health.smc.skku.edu/smc_check/b_myhealth/b01_02/b01_02_03.smc?left=2_3.
31. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Blood circulation [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14661&srchFr=&srchTo=&srchWord=%ED%98%88%ED%96%89&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
32. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Immune function [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 5, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14662&srchFr=&srchTo=&srchWord=&srchTp=&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&page=5.
33. Segerstrom SC. Stress, energy, and immunity: an ecological view. Curr Dir Psychol Sci. 2007; 16(6):326–30.
34. Mendoza-Núñez VM, Ruiz-Ramos M, Sánchez-Rodríguez MA, Retana-Ugalde R, Muñoz-Sánchez JL. Aging-related oxidative stress in healthy humans. Tohoku J Exp Med. 2007; 213(3):261–8.
Article
35. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to support anti-oxidant activity [Internet]. Cheongju: Ministry of Food and Drug Safety; 2012 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=12986&srchFr=&srchTo=&srchWord=%ED%95%AD%EC%82%B0%ED%99%94&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
36. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: Bone health, healthy joint and cartilage [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14658&srchFr=&srchTo=&srchWord=%EA%B8%B0%EB%8A%A5&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
37. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve athletic ability [Internet]. Cheongju: Ministry of Food and Drug Safety; 2016 [cited Apr 25, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=12964&srchFr=&srchTo=&srchWord=%EC%9A%B4%EB%8F%99&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
38. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help maintain prostate health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13242&srchFr=&srchTo=&srchWord=%EC%A0%84%EB%A6%BD%EC%84%A0&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
39. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help to improve bladder function [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 10, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13240&srchFr=&srchTo=&srchWord=%EB%B0%B0%EB%87%A8&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
40. Jeong SJ. Common micturition disorder in the elderly. Korean J Med. 2012; 82(1):98–106.
41. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help with urinary tract health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2017 [cited Apr 15, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=13241&srchFr=&srchTo=&srchWord=%EC%9A%94%EB%A1%9C&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
42. Ministry of Food and Drug Safety. A guideline for functional assessment of health functional food: May help respiratory (respiratorius, bronchus) health [Internet]. Cheongju: Ministry of Food and Drug Safety; 2020 [cited Apr 20, 2021]. Available from: https://www.mfds.go.kr/brd/m_1060/view.do?seq=14603&srchFr=&srchTo=&srchWord=%ED%98%B8%ED%9D%A1%EA%B8%B0&srchTp=0&itm_seq_1=0&itm_seq_2=0&multi_itm_seq=0&company_cd=&company_nm=&Data_stts_gubun=C9999&page=1.
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