Korean J Intern Med.
2022 Feb;37(2):249-260. 10.3904/kjim.2021.403.
The Korean Severe Asthma Registry (KoSAR): real world research in severe asthma
- Kim SH1
- Lee H1
- Park SY2
- Park SY3
- Song WJ4
- Kim JH5
- Park HW6
- Cho YS
4 - Yoon HJ1
- on behalf of the KoSAR investigators1
- Affiliations
-
- 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea
- 2Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
- 3Department of Internal Medicine, Eulji General Hospital, Eulji University School of Medicine, Seoul, Korea
- 4Department of Allergy and Clinical Immunology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
- 5Department of Internal Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea
- 6Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
- KMID: 2527288
- DOI: http://doi.org/10.3904/kjim.2021.403
Abstract
- Severe asthma constitutes a serious health burden with significant morbidity and socioeconomic costs. The development and introduction of new biologics targeting type 2 inflammation changed the paradigm for management of severe asthma and initiated a biological era. These changes impose a challenge to clinicians in managing difficult-to-treat and severe asthma. To understand the characteristics and heterogeneity of severe asthma and to develop a better strategy to manage it, the Korean Academy of Asthma, Allergy and Clinical Immunology, Working Group on Severe Asthma, has organized the Korean Severe Asthma Registry (KoSAR). In this review, we describe the challenges of severe asthma management regarding diagnosis, disease burden, heterogeneity, guidelines, and organization of severe asthma clinics. This review also examines the current global activities of national and regional registries and study groups. In addition, we present the KoSAR vision and organization and describe the findings of KoSAR in comparison with those of other countries.
