Cardiovasc Imaging Asia.  2018 Jan;2(1):12-18. 10.22468/cvia.2017.00185.

Clinical Application of T1 and T2 Mapping in Cardiac Magnetic Resonance Imaging for Nonischemic Cardiomyopathy: A Case-Based Review

Affiliations
  • 1Department of Radiology and Imaging, Muhimbili University of Health and Allied Sciences, Dar Es Salaam, Tanzania
  • 2Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
  • 3Department of Radiology and Research Institute of Radiological Science, Gangnam Severance Hospital, Yonsei University Medical Center, Seoul, Korea

Abstract

Cardiac magnetic resonance imaging is instrumental in diagnosing various cardiovascular diseases. Recently introduced T1 mapping and T2 mapping sequences have enabled quantification of the T1 and T2 relaxation times of the myocardium and associated cardiovascular structures, which are intrinsic properties of tissues. These sequences have been increasingly used to diagnose cardiomyopathy based on changes in the T1 and T2 relaxation times and to objectively quantify the severity of cardiomyopathy. As reference values in T1 and T2 mapping sequences are influenced by specific techniques or magnetic field strength, they are limitations. However, parametric imaging with native T1, T2, and extracellular volume fraction (%) values yields a higher diagnostic accuracy than conventional MRI and is useful for diagnosis, treatment, and risk stratification of cardiomyopathy.

Keyword

T1 mapping; T2 mapping; Extracellular space; Magnetic resonance imaging; Cardiomyopathies
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