J Korean Assoc Oral Maxillofac Surg.  2021 Dec;47(6):471-475. 10.5125/jkaoms.2021.47.6.471.

Solitary plasmacytoma in the maxillary sinus: 10-year follow-up

Affiliations
  • 1Department of Oral and Maxillofacial Surgery, Dental Research Institute, School of Dentistry, Seoul National University, Seoul, Korea

Abstract

Solitary plasmacytoma (SP) is an uncommon form of plasma cell neoplasm occurring intraosseously or in soft tissue and presents as a single mass of monoclonal plasma cells. SP in the maxillary sinus is rare and can be misdiagnosed as other maxillary sinus tumors. The essential examinations in patients with the initial diagnosis of plasmacytoma are bone marrow biopsy, serum and urine electrophoresis, and kappa/lambda ratio (κ:λ ratio) to rule out multiple myeloma (MM). Herein, a rare case of SP in the maxillary sinus treated by surgery and localized radiation is reported. At the 10-year follow-up examination, local recurrence or disseminated development of MM were not evident.

Keyword

Plasmacytoma; Maxillary sinus; Multiple myeloma

Figure

  • Fig. 1 Preoperative panoramic (A), Waters’ view (B), and computed tomography axial view (C) revealed a mass within the right maxillary sinus (arrows). The mass destroyed the anterior, medial, and posterior walls of the sinus and extended into the right nasal cavity.

  • Fig. 2 Panoramic (A) and Waters’ view (B) one month after recession surgery. Panoramic (C) and plain skull (D) views after mesh removal surgery.

  • Fig. 3 Light microscopy photomicrograph of H&E staining of maxillary sinus plasmacytoma. A. Atypical plasma cells with typical cartwheel or clock face heterochromatin arrangement (red arrows) (×200). B. Plasma cells show various stages of maturity with enlarged nuclei and high nucleus-to-cytoplasm ratio (blue arrows) and mitosis (yellow arrows) (×400).


Reference

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