Lab Anim Res.  2021 Dec;37(4):320-323. 10.1186/s42826-021-00106-z.

Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study

  • 1Jeonbuk Branch Institute, Korea Institute of Toxicology, Jeongeup, Republic of Korea
  • 2Molecular Toxicology Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.
  • 3Pharmacology & Drug Abuse Research Group, Korea Institute of Toxicology, Daejeon, Republic of Korea.


Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized.
Case presentation
Herein, we report the case of a living cynomolgus monkey (Macaca fascicularis) that was used for the entire experimental period, instead of euthanasia, after surgical removal of an implanted telemetry system. Radiography was used to determine the status of the implanted telemetry, following which, a repair surgery was performed for removing the system; clinical signs were used to preserve the life of the cynomolgus monkey. Postoperative clinical signs, food consumption, hematology, and serum biochemistry were examined during the 12-month observational period. No abnormal readings or conditions were observed in the subject after implant removal.
This study may be a useful case report for living cynomolgus monkeys in telemetry implantations used throughout the study period. We suggest minimizing the suffering and improving the welfare of these animals.


Cynomolgus monkey; Surgery; Telemetry; Implantation; Welfare
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